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Details on Person The coordination of cell proliferation with cell differentia...
| Class:Id | Summation:1598444 |
|---|---|
| _displayName | The coordination of cell proliferation with cell differentia... |
| _timestamp | 2011-09-12 23:26:25 |
| created | [InstanceEdit:1597913] Higgins, JA, 2007-10-31 |
| modified | [InstanceEdit:1598012] Higgins, JA, 2007-11-01 [InstanceEdit:1598115] Higgins, JA, 2007-11-01 [InstanceEdit:1598125] Higgins, JA, 2007-12-18 [InstanceEdit:1601927] Preece, J, 2011-09-12 |
| text | The coordination of cell proliferation with cell differentiation is influenced by plant hormones, and most known plant hormones have been shown to impact on cell-cycle progression. But at the level of cell-cycle entry, the most important hormone is auxin because its asymmetric distribution pattern within tissues enables the simultaneous induction of cell-cycle entry and the expression of genes that regulate cell-fate determination. The following genes have been shown to be involved in the auxin effects on stem cell maintenance and the regulation of differentiation: PLT1, PLT2, SCR, SHR, SLR, WOX5 and RBR1. Auxin affects key cell cycle genes either directly or indirectly: E2Fa, CYCD3;1, CYCD3;2, ICK1, ICK2, CYC2;4 at the G1/S transition and CDKB2;1, CDKB1;1 at the G2/M transition. As the relationship of these genes with cell cycle regulation is currently under active research, this pathway will be addressed in detail in a later version of Reactome. |
| (summation) | [Pathway:1598637] Cell-cycle entry in response to auxin [Arabidopsis thaliana] |
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No pathways have been reviewed or authored by The coordination of cell proliferation with cell differentia... (1598444)
