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Details on Person Furin cleaves pro-factor IX to factor IX

Class:Id	Reaction:159796
_displayName	Furin cleaves pro-factor IX to factor IX
_doRelease	TRUE
_timestamp	2016-11-10 00:56:31
catalystActivity	[CatalystActivity:156993] serine-type endopeptidase activity of FURIN [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:159817] D'Eustachio, P, 2005-03-17 16:24:57
input	[EntityWithAccessionedSequence:159726] 12xCbxE-3D-F9(29-461) [Golgi lumen] [Homo sapiens]
literatureReference	[LiteratureReference:6807230] PACE/furin can process the vitamin K-dependent pro-factor IX precursor within the secretory pathway
modified	[InstanceEdit:163835] D'Eustachio, P, 2005-05-07 21:30:29 [InstanceEdit:164453] D'Eustachio, P, 2005-05-19 19:30:13 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:6807226] D'Eustachio, Peter, 2015-10-29 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Furin cleaves pro-factor IX to factor IX pro-factor IX -> factor IX + factor IX propeptide
output	[EntityWithAccessionedSequence:159822] 12xCbxE-3D-F9(47-461) [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:159735] factor IX propeptide [Golgi lumen] [Homo sapiens]
precedingEvent	[BlackBoxEvent:159836] Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus [Homo sapiens] [Reaction:159803] GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) [Homo sapiens]
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359757] R-HSA-159796.4
summation	[Summation:179101] Furin, associated with the Golgi membrane, cleaves pro-facto...
(hasEvent)	[Pathway:159782] Removal of aminoterminal propeptides from gamma-carboxylated proteins [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783826] Update Tracker - [Reaction:159796] Furin cleaves pro-factor IX to factor IX - v55:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by Furin cleaves pro-factor IX to factor IX (159796)