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Details on Person Factor IX San Dimas. Substitution of glutamine for Arg-4 in the propeptide leads to incomplete gamma-carboxylation and altered phospholipid binding properties.

Class:Id	LiteratureReference:159725
_displayName	Factor IX San Dimas. Substitution of glutamine for Arg-4 in the propeptide leads to incomplete gamma-carboxylation and altered phospholipid binding properties.
_timestamp	2005-03-17 16:25:27
author	[Person:159829] Ware, J [Person:159804] Diuguid, DL [Person:159807] Liebman, HA [Person:159867] Rabiet, MJ [Person:159799] Kasper, CK [Person:159856] Furie, BC [Person:159805] Furie, B [Person:159724] Stafford, DW
created	[InstanceEdit:159817] D'Eustachio, P, 2005-03-17 16:24:57
journal	J Biol Chem
pages	11401-6
pubMedIdentifier	2738071
title	Factor IX San Dimas. Substitution of glutamine for Arg-4 in the propeptide leads to incomplete gamma-carboxylation and altered phospholipid binding properties.
volume	264
year	1989
(literatureReference)	[Reaction:159803] GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) [Homo sapiens] [Pathway:9673221] Defective F9 activation [Homo sapiens] [FailedReaction:9673223] FIX(29-461) variant is not activated (factor XIa catalyst) [Homo sapiens] [FailedReaction:9673231] GGCX does not gamma-carboxylate 3D-F9(29-461) (pro-factor IX) [Homo sapiens] [Pathway:9673240] Defective gamma-carboxylation of F9 [Homo sapiens] [EntityWithAccessionedSequence:9673217] 3OHD110-F9(29-461) N43Q [endoplasmic reticulum lumen] [Homo sapiens] [CandidateSet:9673225] F9 zymogen variant [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:9673228] F9(29-461) R43Q [extracellular region] [Homo sapiens] [DefinedSet:9673245] 3OHD110-F9(29-461) variant [endoplasmic reticulum lumen] [Homo sapiens] [Summation:9673199] Being a vitamin K‐dependent (VKD) glycoprotein, factor IX (F... List all 13 refering instances
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No pathways have been reviewed or authored by Factor IX San Dimas. Substitution of glutamine for Arg-4 in the propeptide leads to incomplete gamma-carboxylation and altered phospholipid binding properties. (159725)