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Details on Person UniProt:Q9ATY5 UVH3

Class:IdReferenceGeneProduct:1594892
_chainChangeLogchain:1-1479 added on Sat February 7 2015
_displayNameUniProt:Q9ATY5 UVH3
_timestamp2023-11-03 15:13:32
chainchain:1-1479
checksum72F38D472849EE55
commentFUNCTION Putative single-stranded DNA endonuclease involved in nucleotide excision repair (NER) of UV- and oxidative damaged DNA. May make the 3'-incision step in NER. Seems to play a role in senescence program.COFACTOR Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.SUBCELLULAR LOCATION Expressed in all tissues at low levels.SIMILARITY Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
created[InstanceEdit:1592493] Schmidt, EE
descriptionrecommendedName: DNA repair protein UVH3 ecNumber: 3.1.-.- alternativeName: ERCC5 homolog alternativeName: RAD2 homolog shortName: AtRAD2 shortName: AtUVH3 shortName: AtXPG alternativeName: UV hypersensitive protein 3 alternativeName: XPG homolog
geneNameUVH3
RAD2
XPG
At3g28030
MMG15.7
identifierQ9ATY5
isSequenceChangedFALSE
keywordDNA damage
DNA repair
Endonuclease
Hydrolase
Magnesium
Metal-binding
Nuclease
Nucleus
Reference proteome
modified[InstanceEdit:1592494] Croft, D
[InstanceEdit:1592491] Preece, J, 2011-09-12
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameUVH3
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:1595771] KEGG Gene:AT3G28030 AT3G28030 [Arabidopsis thaliana]
[ReferenceDNASequence:1595772] ENSEMBL Plant:AT3G28030 [Arabidopsis thaliana]
[ReferenceDNASequence:1595773] TAIR:AT3G28030 [Arabidopsis thaliana]
secondaryIdentifierUVH3_ARATH
Q9LRT2
sequenceLength1479
species[Species:170905] Arabidopsis thaliana
(referenceEntity)[EntityWithAccessionedSequence:1593485] Q9ATY5 [nucleoplasm] [Arabidopsis thaliana]
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No pathways have been reviewed or authored by UniProt:Q9ATY5 UVH3 (1594892)