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Details on Person benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate

Class:Id	Reaction:159443
_displayName	benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate
_doRelease	TRUE
_timestamp	2016-11-10 00:56:54
authored	[InstanceEdit:159444] Jassal, B, 2005-03-10 15:37:26
catalystActivity	[CatalystActivity:177146] CoA-ligase activity of xenobiotic/medium-chain fatty acid:CoA ligases [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:159444] Jassal, B, 2005-03-10 15:37:26
input	[SimpleEntity:159446] BENZA [mitochondrial matrix] [SimpleEntity:113593] ATP [mitochondrial matrix] [SimpleEntity:29374] CoA-SH [mitochondrial matrix]
literatureReference	[LiteratureReference:159552] Isolation, sequencing, and expression of a cDNA for the HXM-A form of xenobiotic/medium-chain fatty acid:CoA ligase from human liver mitochondria [LiteratureReference:159570] Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acids
modified	[InstanceEdit:159571] Jassal, B, 2005-03-11 11:58:02 [InstanceEdit:177120] D'Eustachio, P, 2006-03-23 20:05:02 [InstanceEdit:177163] D'Eustachio, P, 2006-03-23 20:35:35 [InstanceEdit:177295] D'Eustachio, P, 2006-03-27 18:47:31 [InstanceEdit:211333] D'Eustachio, P, 2008-01-31 19:12:03 [InstanceEdit:353652] Jassal, Bijay, 2008-06-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate Benzoate and Coenzyme A react to form benzoyl-CoA thioester
output	[SimpleEntity:159447] BEZ-CoA [mitochondrial matrix] [SimpleEntity:159448] AMP [mitochondrial matrix] [SimpleEntity:159450] PPi [mitochondrial matrix]
releaseDate	2006-04-24
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361396] R-HSA-159443.3
summation	[Summation:177156] Benzoate and ATP react with coenzyme A to form benzoyl CoA, ...
(hasEvent)	[Pathway:177135] Conjugation of benzoate with glycine [Homo sapiens]
(precedingEvent)	[Reaction:159566] benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A [Homo sapiens]
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No pathways have been reviewed or authored by benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (159443)