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Details on Person Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)

Class:Id	Reaction:159425
_displayName	Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)
_doRelease	TRUE
_timestamp	2010-03-01 15:04:00
authored	[InstanceEdit:159408] Jassal, B, 2005-03-09 13:42:30
catalystActivity	[CatalystActivity:192026] long-chain fatty acid-CoA ligase activity of SLC27A5 [endoplasmic reticulum membrane]
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:159408] Jassal, B, 2005-03-09 13:42:30
edited	[InstanceEdit:194157] D'Eustachio, P, 2007-03-09 21:29:31
input	[DefinedSet:194096] CCA,CDCA [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:76194] CoA-SH [cytosol]
literatureReference	[LiteratureReference:193432] Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling
modified	[InstanceEdit:159430] Jassal, B, 2005-03-09 14:53:32 [InstanceEdit:194078] D'Eustachio, P, 2007-03-08 15:03:08 [InstanceEdit:194163] D'Eustachio, P, 2007-03-09 21:33:16 [InstanceEdit:195718] Gopinathrao, G, 2007-04-16 17:35:22 [InstanceEdit:197014] Gopinathrao, G, 2007-04-30 12:01:02 [InstanceEdit:197116] D'Eustachio, P, 2007-04-30 14:50:16 [InstanceEdit:532572] D'Eustachio, P, 2010-03-01 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)
output	[DefinedSet:194073] choloyl-CoA; chenodeoxycholoyl-CoA [cytosol] [SimpleEntity:76577] AMP [cytosol] [SimpleEntity:111294] PPi [cytosol] [SimpleEntity:29356] H2O [cytosol]
precedingEvent	[Reaction:194130] Transport (influx) of bile salts and acids by OATP-A [Homo sapiens] [Reaction:194153] ABCC3 transports bile salts from cytosol to extracellular region [Homo sapiens]
releaseDate	2007-05-15
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359364] R-HSA-159425.2
summation	[Summation:194123] Cholate or chenodeoxycholate, coenzyme A, and ATP react to f...
(hasEvent)	[Pathway:159418] Recycling of bile acids and salts [Homo sapiens]
(precedingEvent)	[Reaction:159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine [Homo sapiens]
(replacementInstances)	[_Deleted:194071] Deletion of instance: 159423
(updatedInstance)	[_UpdateTracker:9791119] Update Tracker - [Reaction:159425] Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) - v32:[addInput]
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