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Details on Person Expression of POLRMT

Class:Id	BlackBoxEvent:1592243
_displayName	Expression of POLRMT
_doRelease	TRUE
_timestamp	2018-10-31 14:28:09
authored	[InstanceEdit:1592225] May, B, 2011-08-20
compartment	[Compartment:7660] nucleoplasm [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1592237] May, B, 2011-09-09
edited	[InstanceEdit:1592225] May, B, 2011-08-20
input	[EntityWithAccessionedSequence:4686134] POLRMT gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1592174] Nuclear respiratory factor 2 induces the expression of many but not all human proteins acting in mitochondrial DNA transcription and replication [LiteratureReference:1605450] Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin
modified	[InstanceEdit:1605406] May, B, 2011-09-21 [InstanceEdit:3108240] May, B, 2013-02-10 [InstanceEdit:3189817] May, B, 2013-02-25 [InstanceEdit:4410479] May, B, 2013-08-23 [InstanceEdit:4420247] May, B, 2013-08-31 [InstanceEdit:4686154] May, B, 2013-10-11 [InstanceEdit:5210064] May, B, 2013-12-07 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9627000] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of POLRMT
output	[EntityWithAccessionedSequence:163267] POLRMT [mitochondrial matrix] [Homo sapiens]
precedingEvent	[Reaction:1592240] Formation of NRF2 [Homo sapiens] [BlackBoxEvent:1592234] Expression of GABPA (NRF2 alpha subunit) [Homo sapiens]
regulatedBy	[PositiveRegulation:1592260] Positive regulation by 'NRF2 [nucleoplasm]'
regulationReference	[RegulationReference:9641973] Positive regulation by 'NRF2 [nucleoplasm]' Nuclear respiratory factor 2 induces the expression of many but not all human proteins acting in mitochondrial DNA transcription and replication
releaseDate	2014-03-12
reviewed	[InstanceEdit:5210062] Lezza, Angela M S, 2013-12-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645015] R-HSA-1592243.5
summation	[Summation:1605469] The POLRMT (mitochondrial RNA polymerase) gene is transcribe...
(hasEvent)	[Pathway:2151201] Transcriptional activation of mitochondrial biogenesis [Homo sapiens]
(precedingEvent)	[Reaction:163296] Association of TFAM:mt promoter complex with POLRMT:TFB2M [Homo sapiens] [Reaction:9986307] POLRMT binds TFAM:mitochondrial promoter [Homo sapiens]
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No pathways have been reviewed or authored by Expression of POLRMT (1592243)