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Details on Person Expression of NRF1

Class:Id	BlackBoxEvent:1592242
_displayName	Expression of NRF1
_doRelease	TRUE
_timestamp	2014-11-20 02:33:23
authored	[InstanceEdit:1592225] May, B, 2011-08-20
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1592237] May, B, 2011-09-09
edited	[InstanceEdit:1592225] May, B, 2011-08-20
input	[EntityWithAccessionedSequence:4686148] NRF1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1605510] Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1
modified	[InstanceEdit:1605406] May, B, 2011-09-21 [InstanceEdit:3108240] May, B, 2013-02-10 [InstanceEdit:3189817] May, B, 2013-02-25 [InstanceEdit:4410479] May, B, 2013-08-23 [InstanceEdit:4420247] May, B, 2013-08-31 [InstanceEdit:4686154] May, B, 2013-10-11 [InstanceEdit:5210064] May, B, 2013-12-07 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of NRF1
output	[EntityWithAccessionedSequence:1592205] NRF1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:1592244] AMPK phosphorylates PPARGC1A [Homo sapiens] [Reaction:380930] Phosphorylated AMPK binds AMP [Homo sapiens] [Reaction:1592233] p38 MAPK phosphorylates PPARGC1A [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:1592269] Positive gene expression regulation by 'p-PPARGC1A [nucleoplasm]'
regulationReference	[RegulationReference:9642411] Positive gene expression regulation by 'p-PPARGC1A [nucleoplasm]' Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
releaseDate	2014-03-12
reviewed	[InstanceEdit:5210062] Lezza, Angela M S, 2013-12-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644296] R-HSA-1592242.4
summation	[Summation:1605525] The NRF1 gene is transcribed to yield mRNA and the mRNA is t...
(hasEvent)	[Pathway:2151201] Transcriptional activation of mitochondrial biogenesis [Homo sapiens]
(precedingEvent)	[Reaction:1592236] NRF1:p-PPARGC1A, NRF2 bind the TFB1M promoter [Homo sapiens] [Reaction:1592245] NRF1:PPARGC1B binds the ALAS1 promoter [Homo sapiens] [Reaction:1592249] NRF1, PPRC1, NRF2 bind the TFAM promoter [Homo sapiens] [Reaction:2466369] NRF1:PPARGC1B binds the ATP5B promoter [Homo sapiens] [Reaction:2466370] NRF1:PPARGC1B binds the CYCS promoter [Homo sapiens] [Reaction:2466391] NRF1:p-PPARGC1A, NRF2 bind the TFAM promoter [Homo sapiens] [Reaction:2466392] NRF1:p-PPARGC1A, NRF2 bind the TFB2M promoter [Homo sapiens]
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No pathways have been reviewed or authored by Expression of NRF1 (1592242)