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Details on Person TFAM translocates from the cytosol to the mitochondrial matrix

Class:Id	BlackBoxEvent:1592229
_displayName	TFAM translocates from the cytosol to the mitochondrial matrix
_doRelease	TRUE
_timestamp	2014-11-20 02:40:33
authored	[InstanceEdit:1592225] May, B, 2011-08-20
compartment	[Compartment:70101] cytosol [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1592237] May, B, 2011-09-09
edited	[InstanceEdit:1592225] May, B, 2011-08-20
inferredFrom	[BlackBoxEvent:1606727] Tfam translocates from the cytosol to the mitochondrial matrix [Rattus norvegicus]
input	[EntityWithAccessionedSequence:1592203] TFAM(1-246) [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5210054] Mitochondrial preprotein translocases as dynamic molecular machines
modified	[InstanceEdit:1605406] May, B, 2011-09-21 [InstanceEdit:1606720] May, B, 2011-09-25 [InstanceEdit:3108240] May, B, 2013-02-10 [InstanceEdit:3189817] May, B, 2013-02-25 [InstanceEdit:4410479] May, B, 2013-08-23 [InstanceEdit:4420247] May, B, 2013-08-31 [InstanceEdit:5210064] May, B, 2013-12-07 [InstanceEdit:5256664] May, B, 2014-02-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TFAM translocates from the cytosol to the mitochondrial matrix
output	[EntityWithAccessionedSequence:163312] TFAM [mitochondrial matrix] [Homo sapiens]
precedingEvent	[BlackBoxEvent:1592246] Expression of TFAM [Homo sapiens] [Reaction:1592249] NRF1, PPRC1, NRF2 bind the TFAM promoter [Homo sapiens] [Reaction:2466391] NRF1:p-PPARGC1A, NRF2 bind the TFAM promoter [Homo sapiens]
releaseDate	2014-03-12
reviewed	[InstanceEdit:5210062] Lezza, Angela M S, 2013-12-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644554] R-HSA-1592229.2
summation	[Summation:1605541] TFAM is encoded in the nucleus, synthesized as a precursor i...
(hasEvent)	[Pathway:2151201] Transcriptional activation of mitochondrial biogenesis [Homo sapiens]
(precedingEvent)	[Reaction:163310] TFAM binds to mitochondrial promoters [Homo sapiens]
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No pathways have been reviewed or authored by TFAM translocates from the cytosol to the mitochondrial matrix (1592229)