Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Bilirubin (BIL) is a breakdown product of heme. Its accumula...
| Class:Id | Summation:159166 |
|---|---|
| _displayName | Bilirubin (BIL) is a breakdown product of heme. Its accumula... |
| _timestamp | 2020-10-19 12:16:30 |
| created | [InstanceEdit:159184] Jassal, B, 2005-02-23 15:02:50 |
| modified | [InstanceEdit:699800] D'Eustachio, P, 2010-05-08 [InstanceEdit:5604980] Jassal, Bijay, 2014-07-03 [InstanceEdit:5622022] Jassal, Bijay, 2014-09-08 [InstanceEdit:9702655] Jassal, Bijay, 2020-10-01 [InstanceEdit:9704995] Jassal, Bijay, 2020-10-19 |
| text | Bilirubin (BIL) is a breakdown product of heme. Its accumulation in the blood can be fatal. It is highly lipophilic and thus requires conjugation to become more water soluble to aid excretion. Both UGT1A1 tetramer and UGT1A4 can transfer glucuronic acid (GlcA) to bilirubin to form either its monoglucuronide (BMG) or diglucuronide (BDG) conjugates (Bosma et al. 1994, Ritter et al. 1992, Peters & Jansen 1986, Gorden et al. 1983, Choudhury et al. 1981, Fevery et al. 1971). |
| (summation) | [Reaction:159194] UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG [Homo sapiens] [Reaction:9632039] UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Bilirubin (BIL) is a breakdown product of heme. Its accumula... (159166)
