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Details on Person Plasminogen, tethered to the cell surface by its association...
| Class:Id | Summation:158967 |
|---|---|
| _displayName | Plasminogen, tethered to the cell surface by its association... |
| _timestamp | 2005-02-14 18:06:33 |
| created | [InstanceEdit:158962] D'Eustachio, P, 2005-02-14 18:06:15 |
| literatureReference | [LiteratureReference:158966] Plasminogen activation initiated by single-chain urokinase-type plasminogen activator. Potentiation by U937 monocytes. [LiteratureReference:158936] Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor. |
| text | Plasminogen, tethered to the cell surface by its association with histidine-rich glycoprotein, is rapidly cleaved and activated to plasmin by the action of urokinase plasminogen activator(two-chain form) bound to uPAR, its cell-surface receptor. The association of both substrate and enzyme with the cell surface is necessary for the reaction to proceed efficiently (Ellis et al. 1989, 1991). |
| (summation) | [Reaction:158925] plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) [Homo sapiens] |
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No pathways have been reviewed or authored by Plasminogen, tethered to the cell surface by its association... (158967)
