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Details on Person Interaction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger and the kringle-2 domain of t-PA.

Class:IdLiteratureReference:158798
_displayNameInteraction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger and the kringle-2 domain of t-PA.
_timestamp2005-02-08 22:51:22
author[Person:158793] Wagner, OF
[Person:158790] de Vries, C
[Person:158794] Hohmann, C
[Person:158792] Veerman, H
[Person:158801] Pannekoek, H
created[InstanceEdit:158796] D'Eustachio, P, 2005-02-08 22:51:14
journalJ Clin Invest
pages647-55
pubMedIdentifier2503541
titleInteraction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger and the kringle-2 domain of t-PA.
volume84
year1989
(literatureReference)[Reaction:158795] fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 [Homo sapiens]
[Reaction:158800] fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 [Homo sapiens]
[Summation:158799] Plasminogen activator inhibitor 1, a serpin, binds to fibrin...
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No pathways have been reviewed or authored by Interaction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger and the kringle-2 domain of t-PA. (158798)