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Details on Person fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1

Class:Id	Reaction:158795
_displayName	fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1
_doRelease	TRUE
_timestamp	2016-11-10 00:57:00
authored	[InstanceEdit:158796] D'Eustachio, P, 2005-02-08 22:51:14
catalystActivity	[CatalystActivity:158919] serine-type endopeptidase inhibitor activity of SERPINE1-like proteins [extracellular region]
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:158796] D'Eustachio, P, 2005-02-08 22:51:14
edited	[InstanceEdit:165080] D'Eustachio, P, 0000-00-00 00:00:00
input	[Complex:158764] fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:158797] SERPINE1 [extracellular region] [Homo sapiens]
literatureReference	[LiteratureReference:158798] Interaction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger and the kringle-2 domain of t-PA.
modified	[InstanceEdit:158921] D'Eustachio, P, 2005-02-14 18:02:50 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1
output	[Complex:158791] fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:158781] crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) [Homo sapiens] [BlackBoxEvent:140851] fibrin multimer -> fibrin multimer, crosslinked + NH4+ [Homo sapiens]
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:362062] R-HSA-158795.3
summation	[Summation:158799] Plasminogen activator inhibitor 1, a serpin, binds to fibrin...
(hasEvent)	[Pathway:75205] Dissolution of Fibrin Clot [Homo sapiens]
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No pathways have been reviewed or authored by fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 (158795)