Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Once plasmin has been activated, in the initial stage of the...

Class:IdSummation:158759
_displayNameOnce plasmin has been activated, in the initial stage of the...
_timestamp2005-02-08 21:37:04
created[InstanceEdit:158778] D'Eustachio, P, 2005-02-08 21:36:34
literatureReference[LiteratureReference:158782] Interaction of one-chain and two-chain tissue plasminogen activator with intact and plasmin-degraded fibrin
[LiteratureReference:158752] The single-chain form of tissue-type plasminogen activator has catalytic activity: studies with a mutant enzyme that lacks the cleavage site
textOnce plasmin has been activated, in the initial stage of the fibrinolysis process, it can catalyze the conversion of fibrin-bound tissue plasminogen activator (one-chain) to its more active two-chain form, increasing the rate at which additional plasminogen molecules can be activated.
(summation)[Reaction:158747] crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) [Homo sapiens]
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No pathways have been reviewed or authored by Once plasmin has been activated, in the initial stage of the... (158759)