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Details on Person crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin

Class:Id	Reaction:158744
_displayName	crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin
_doRelease	TRUE
_timestamp	2016-11-10 00:57:14
catalystActivity	[CatalystActivity:158767] serine-type endopeptidase activity of fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen [extracellular region]
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:158778] D'Eustachio, P, 2005-02-08 21:36:34
input	[Complex:158786] fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen [extracellular region] [Homo sapiens]
literatureReference	[LiteratureReference:158782] Interaction of one-chain and two-chain tissue plasminogen activator with intact and plasmin-degraded fibrin [LiteratureReference:158787] Characterization of the gene for human plasminogen, a key proenzyme in the fibrinolytic system
modified	[InstanceEdit:159018] D'Eustachio, P, 2005-02-14 18:46:02 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin
output	[Complex:158745] fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) [extracellular region] [Homo sapiens] [Complex:158770] Plasmin [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:158756] crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen [Homo sapiens] [Reaction:158747] crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) [Homo sapiens]
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360459] R-HSA-158744.3
summation	[Summation:178563] At the beginning of this reaction, 1 molecule of 'fibrin mul...
(hasEvent)	[Pathway:75205] Dissolution of Fibrin Clot [Homo sapiens]
(precedingEvent)	[Reaction:158766] fibrin multimer, crosslinked -> fibrin digestion products (plasmin) [Homo sapiens] [Reaction:158893] alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin [Homo sapiens]
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No pathways have been reviewed or authored by crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin (158744)