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Details on Person factor VIIIa:factor IXa [plasma membrane]

Class:Id	Complex:158392
_displayName	factor VIIIa:factor IXa [plasma membrane]
_timestamp	2014-11-18 09:19:39
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:158298] D'Eustachio, P, 2005-01-20 14:44:36
hasComponent	[Complex:5633116] factor VIIIa [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:158121] F8(20-391) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:158144] F8(392-759) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:158388] F8(1709-2351) [plasma membrane] [Homo sapiens] [Complex:5633117] factor IXa [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:158225] HC-335-F9(227-461) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:140894] 12xCbxE-3D-HC-C178-F9(47-191) [plasma membrane] [Homo sapiens]
modified	[InstanceEdit:5607040] Jupe, Steve, 2014-07-09 [InstanceEdit:5627268] Jupe, Steve, 2014-10-17 [InstanceEdit:5627268] Jupe, Steve, 2014-10-17 [InstanceEdit:5643852] Jupe, Steve, 2014-11-18
name	factor VIIIa:factor IXa
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:365194] R-HSA-158392.1
(hasComponent)	[Complex:9669957] FVIIIa:FIXa:PROS1 [plasma membrane] [Homo sapiens]
(input)	[Reaction:9669959] Factor IXa binds protein S [Homo sapiens]
(normalEntity)	[EntityFunctionalStatus:9668252] gain_of_function of FVIIIa:FIXa R384L [plasma membrane] [EntityFunctionalStatus:9668371] loss_of_function of FVIIIa variant:FIXa [plasma membrane] [EntityFunctionalStatus:9670879] loss_of_function of factor VIIIa:factor IXa variant [plasma membrane]
(output)	[Reaction:158278] factor VIIIa + factor IXa -> factor VIIIa:factor IXa [Homo sapiens]
(physicalEntity)	[CatalystActivity:158179] serine-type endopeptidase activity of factor VIIIa:factor IXa [plasma membrane]
(updatedInstance)	[_UpdateTracker:9939932] Update Tracker - [Complex:158392] factor VIIIa:factor IXa [plasma membrane] - v92:[updateContainedComponent]
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No pathways have been reviewed or authored by factor VIIIa:factor IXa [plasma membrane] (158392)