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Details on Person Identification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator

Class:IdLiteratureReference:158237
_displayNameIdentification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator
_timestamp2005-01-20 14:45:29
author[Person:158302] Shariat-Madar, Z
[Person:158403] Mahdi, F
[Person:140269] Schmaier, AH
created[InstanceEdit:158298] D'Eustachio, P, 2005-01-20 14:44:36
journalJ Biol Chem
pages17962-9
pubMedIdentifier11830581
titleIdentification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator
volume277
year2002
(literatureReference)[Reaction:158251] OBSOLETE_prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer_REPLACMENT_9857945 [Homo sapiens]
[Reaction:9857945] prekallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1-> kallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1 (PRCP catalyst) [Homo sapiens]
[RegulationReference:9857955] Positive regulation by 'PRCP [plasma membrane]' Prolylcarboxypeptidase independently activates plasma prekallikrein (fletcher factor)
[CatalystActivityReference:9938550] serine-type carboxypeptidase activity of prolylcarboxypeptidase dimer [plasma membrane] Identification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator
[Summation:158190] This Reactome event shows plasma kallikrein (PKa)-mediated c...
[Summation:158329] Factor XI, bound to the cell surface, is converted to activa...
[Summation:158383] Prekallikrein in a complex with kininogen and C1q binding pr...
[Summation:9857899] Autocatalytic cleavage of a single peptide bond after Arg372...
[Summation:9857962] Surface-bound prekallikrein (PK), encoded by the KLKB1 gene ...
[Summation:9857963] The plasma kallikrein-kinin system (KKS) is a proteolytic ca...
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