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Details on Person High molecular weight kininogen regulates prekallikrein assembly and activation on endothelial cells: a novel mechanism for contact activation

Class:IdLiteratureReference:158182
_displayNameHigh molecular weight kininogen regulates prekallikrein assembly and activation on endothelial cells: a novel mechanism for contact activation
_timestamp2005-01-20 14:45:20
author[Person:158288] Motta, G
[Person:158297] Rojkjaer, R
[Person:158421] Hasan, AA
[Person:158127] Cines, DB
[Person:140269] Schmaier, AH
created[InstanceEdit:158298] D'Eustachio, P, 2005-01-20 14:44:36
journalBlood
pages516-28
pubMedIdentifier9427705
titleHigh molecular weight kininogen regulates prekallikrein assembly and activation on endothelial cells: a novel mechanism for contact activation
volume91
year1998
(literatureReference)[Reaction:158218] OBSOLETE_prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer_REPLACEMENT_9857939_9857952 [Homo sapiens]
[Reaction:158311] OBSOLETE_kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin_REPLACEMENT_9938539 [Homo sapiens]
[Reaction:9857939] prekallikrein + kininogen -> prekallikrein:kininogen [Homo sapiens]
[Reaction:9857952] prekallikrein:kininogen binds cell surface receptors [Homo sapiens]
[Reaction:9938539] kallikrein:kininogen:cell surface receptor -> kallikrein + cleaved kininogen:cell surface receptor + bradykinin [Homo sapiens]
[Summation:158244] Prekallikrein (PK) associates specifically with kininogen (H...
[Summation:158393] The cleavage of kininogen (HK, high molecular weight kininog...
[Summation:9855753] The contact activation system (CAS) is a plasma serine prote...
[Summation:9857944] The prekallikrein (PK):kininogen (HK) complex, KLKB1(20–638)...
[Summation:9857962] Surface-bound prekallikrein (PK), encoded by the KLKB1 gene ...
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