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Details on Person Plasma kallikrein [extracellular region]

Class:Id	Complex:158140
_displayName	Plasma kallikrein [extracellular region]
_timestamp	2011-09-14 15:47:59
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:158298] D'Eustachio, P, 2005-01-20 14:44:36
hasComponent	[EntityWithAccessionedSequence:158239] KLKB1(20-390) [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:158181] KLKB1(391-638) [extracellular region] [Homo sapiens]
modified	[InstanceEdit:167229] D'Eustachio, P, 2005-10-13 14:50:40 [InstanceEdit:1602467] Jupe, S, 2011-09-14
name	Plasma kallikrein
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:368339] R-HSA-158140.1
(hasComponent)	[Complex:158334] kallikrein:alpha2-macroglobulin [extracellular region] [Homo sapiens] [Complex:158423] kallikrein:C1Inh [extracellular region] [Homo sapiens]
(hasMember)	[DefinedSet:1602468] proMMP1 initial activators [extracellular region] [Homo sapiens] [DefinedSet:1604721] proMMP3 initial activators [extracellular region] [Homo sapiens]
(input)	[Reaction:158340] kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin [Homo sapiens] [Reaction:158399] kallikrein binds SERPING1 [Homo sapiens] [FailedReaction:9651467] SERPING1 variant does not bind kallikrein [Homo sapiens]
(output)	[Reaction:158311] OBSOLETE_kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin_REPLACEMENT_9938539 [Homo sapiens] [Reaction:9938539] kallikrein:kininogen:cell surface receptor -> kallikrein + cleaved kininogen:cell surface receptor + bradykinin [Homo sapiens]
(physicalEntity)	[CatalystActivity:9655044] serine-type endopeptidase activity of Plasma kallikrein [extracellular region]
(updatedInstance)	[_UpdateTracker:9871141] Update Tracker - [Complex:158140] Plasma kallikrein [extracellular region] - v39:[modifyName]
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No pathways have been reviewed or authored by Plasma kallikrein [extracellular region] (158140)