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Details on Person VWF multimer [extracellular region]

Class:IdComplex:158136
_displayNameVWF multimer [extracellular region]
_timestamp2024-11-29 14:53:34
compartment[Compartment:984] extracellular region
created[InstanceEdit:158298] D'Eustachio, P, 2005-01-20 14:44:36
hasComponent
modified[InstanceEdit:9929868] Shamovsky, Veronica, 2024-11-29
nameVWF multimer
von Willebrand factor multimer
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:362562] R-HSA-158136.2
(hasComponent)[Complex:9822536] Collagen type I fibril:VWF multimer [extracellular region] [Homo sapiens]
(input)[Reaction:158118] factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer [Homo sapiens]
[FailedReaction:9665809] F8 variant does not bind von Willebrand factor [Homo sapiens]
[Reaction:9822539] VWF multimer binds to collagen type I [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:9823613] loss_of_function of VWF A3 domain variant multimer [extracellular region]
(output)[Reaction:158137] factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer [Homo sapiens]
[Reaction:9822522] factor VIII -> factor VIIIa + factor VIII B chain+ factor VIII A3 acidic polypeptide +VWF multimer (TF:FVIIa:FXa catalyst) [Homo sapiens]
(updatedInstance)[_UpdateTracker:9939855] Update Tracker - [Complex:158136] VWF multimer [extracellular region] - v92:[modifyName]
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No pathways have been reviewed or authored by VWF multimer [extracellular region] (158136)