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Query author contributions in Reactome

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Details on Person NICD1 [nucleoplasm]

Class:IdEntityWithAccessionedSequence:157939
_displayNameNICD1 [nucleoplasm]
_timestamp2013-05-09 15:03:36
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:157631] Jassal, B, 2005-01-04 16:01:41
endCoordinate2555
modified[InstanceEdit:210826] D'Eustachio, P, 2008-01-17 00:37:13
[InstanceEdit:419741] D'Eustachio, P, 2009-05-06 14:53:16
[InstanceEdit:1460340] Orlic-Milacic, M, 2011-07-26
[InstanceEdit:2193054] Orlic-Milacic, M, 2012-04-11
[InstanceEdit:2272825] Orlic-Milacic, M, 2012-05-25
[InstanceEdit:3322333] Wu, G, 2013-05-03
[InstanceEdit:3322334] Wu, G, 2013-05-03
[InstanceEdit:3325515] Orlic-Milacic, M, 2013-05-09
nameNICD1
NOTCH1(1754-2555)
NICD 1 fragment
NOTCH1 intracellular domain
N1ICD
referenceEntity[ReferenceGeneProduct:60520] UniProt:P46531 NOTCH1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:366066] R-HSA-157939.1
startCoordinate1754
(activeUnit)[PositiveGeneExpressionRegulation:9762090] Positive gene expression regulation by 'NFE2L2 gene:NICD1 [nucleoplasm]'
(hasComponent)[Complex:1604460] NICD1:RBPJ:SNW1 [nucleoplasm] [Homo sapiens]
[Complex:1911469] NICD1:HIF1A [nucleoplasm] [Homo sapiens]
[Complex:9667653] NICD1:NBEA [nucleoplasm] [Homo sapiens]
[Complex:9762079] NFE2L2 gene:NICD1 [nucleoplasm] [Homo sapiens]
[Complex:9824247] RBPJ:NICD1 [nucleoplasm] [Homo sapiens]
[Complex:9917549] RBPJ:NICD1:MAML1:DLL4 gene [nucleoplasm] [Homo sapiens]
(hasMember)[DefinedSet:212420] NICD [nucleoplasm] [Homo sapiens]
[DefinedSet:9977596] NICD1,2 [nucleoplasm] [Homo sapiens]
(input)[Reaction:1912388] NICD1 displaces co-repressor complex from RBPJ (CSL) [Homo sapiens]
[Reaction:1912396] NICD1 binds HIF1A [Homo sapiens]
[Reaction:2064264] NICD1 displaces NCOR co-repressor complex from CSL [Cercopithecus aethiops]
[Reaction:9667657] NBEA binds NICD1 [Homo sapiens]
[Reaction:9762102] NICD1 binds the NFE2L2 promoter [Homo sapiens]
[Reaction:9824266] LEF1:CTNNB1, NICD1 (NOTCH1) and TBX6 bind the HES7 gene in presomitic mesoderm [Homo sapiens]
[Reaction:9917553] RBPJ, NICD1, and MAML1 bind the DLL4 gene in endothelial tip cell [Homo sapiens]
[Reaction:9979250] NICD1 and coactivators displace corepressors from RBPJ:SNW1:HES1 gene [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:2775826] gain_of_function of NICD1 PEST Domain Mutants [nucleoplasm]
(output)[Reaction:157926] NICD1 traffics to nucleus [Homo sapiens]
[BlackBoxEvent:9980944] NICD1 translocates from the cytosol to nucleus [Homo sapiens]
(physicalEntity)[PhysicalEntityCellType:9979134] NICD1 [nucleoplasm] in endothelial tip cell
[PhysicalEntityCellType:9980920] NICD1 [nucleoplasm] in endothelial stalk cell
(regulator)[PositiveGeneExpressionRegulation:210855] Positive gene expression regulation by 'NICD1 [nucleoplasm]'
(replacementInstances)[_Deleted:2123512] Deletion of instance: 186472
(updatedInstance)[_UpdateTracker:9866634] Update Tracker - [EntityWithAccessionedSequence:157939] NICD1 [nucleoplasm] - v24:[addName]
[_UpdateTracker:9870884] Update Tracker - [EntityWithAccessionedSequence:157939] NICD1 [nucleoplasm] - v38:[addName]
[_UpdateTracker:9872640] Update Tracker - [EntityWithAccessionedSequence:157939] NICD1 [nucleoplasm] - v41:[addName, modifyEndCoordinate, modifyStartCoordinate]
[_UpdateTracker:9885000] Update Tracker - [EntityWithAccessionedSequence:157939] NICD1 [nucleoplasm] - v45:[addName]
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No pathways have been reviewed or authored by NICD1 [nucleoplasm] (157939)
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