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Details on Person JAG1 [plasma membrane]

Class:IdEntityWithAccessionedSequence:157098
_displayNameJAG1 [plasma membrane]
_timestamp2012-01-06 14:54:18
compartment[Compartment:876] plasma membrane
created[InstanceEdit:157021] Jassal, B, 2004-12-15 13:08:03
endCoordinate1218
modified[InstanceEdit:258120] Schmidt, EE, 2008-03-27 09:04:40
[InstanceEdit:1852564] Orlic-Milacic, M, 2011-10-28
[InstanceEdit:2032256] Orlic-Milacic, M, 2012-01-06
nameJAG1
Jagged 1 ligand
referenceEntity[ReferenceGeneProduct:57641] UniProt:P78504 JAG1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:371757] R-HSA-157098.1
startCoordinate34
(entityOnOtherCell)[Reaction:1980042] NOTCH1 binds JAG1 [Homo sapiens]
[Reaction:1980056] JAG1 binds NOTCH2 [Homo sapiens]
[FailedReaction:2660822] NOTCH1 t(7;9)(NOTCH1:M1580_K2555) does not bind JAG1 [Homo sapiens]
[Reaction:2691226] NOTCH1 HD domain mutants bind JAG1 [Homo sapiens]
[Reaction:2768999] NOTCH1 PEST domain mutants bind JAG1 [Homo sapiens]
[Reaction:2900743] NOTCH1 HD+PEST domain mutants bind JAG1 [Homo sapiens]
[Reaction:9604247] JAG1 binds NOTCH4 [Homo sapiens]
[Complex:157008] JAG1:NOTCH1 [plasma membrane] [Homo sapiens]
[Complex:157132] JAG1:NOTCH3 [plasma membrane] [Homo sapiens]
[Complex:1980058] JAG1:NOTCH2 [plasma membrane] [Homo sapiens]
List all 22 refering instances
(hasCandidate)[CandidateSet:9013178] RAC1 effectors [cytosol] [Homo sapiens]
[CandidateSet:9020391] RAC3 effectors [cytosol] [Homo sapiens]
[CandidateSet:9911710] DLL1, (DLL4, JAG1, JAG2) [plasma membrane] [Homo sapiens]
(hasComponent)[Complex:157008] JAG1:NOTCH1 [plasma membrane] [Homo sapiens]
[Complex:157009] NTM-NEC2-Jagged1 complex [extracellular region] [Homo sapiens]
[Complex:157132] JAG1:NOTCH3 [plasma membrane] [Homo sapiens]
[Complex:1980058] JAG1:NOTCH2 [plasma membrane] [Homo sapiens]
[Complex:2691215] JAG1:NOTCH1 HD domain mutants [plasma membrane] [Homo sapiens]
[Complex:2731154] JAG1:NOTCH1 HD domain mutant fragments [extracellular region] [Homo sapiens]
[Complex:2769002] JAG1:NOTCH1 PEST Domain Mutants [plasma membrane] [Homo sapiens]
[Complex:2900751] JAG1:NOTCH1 HD+PEST Domain Mutants [plasma membrane] [Homo sapiens]
[Complex:2902218] JAG1:NOTCH1 HD+PEST Domain Mutant Fragments [plasma membrane] [Homo sapiens]
[Complex:9604245] JAG1:NOTCH4 [plasma membrane] [Homo sapiens]
List all 11 refering instances
(hasMember)[DefinedSet:157643] DLL/JAG [plasma membrane] [Homo sapiens]
(input)[Reaction:157033] NTM-NEC 2 receptor interacts with ligand Jagged1 in the intracellular space [Homo sapiens]
[Reaction:157100] NOTCH3 binds JAG1 [Homo sapiens]
[Reaction:1980042] NOTCH1 binds JAG1 [Homo sapiens]
[Reaction:1980056] JAG1 binds NOTCH2 [Homo sapiens]
[FailedReaction:2660822] NOTCH1 t(7;9)(NOTCH1:M1580_K2555) does not bind JAG1 [Homo sapiens]
[Reaction:2691226] NOTCH1 HD domain mutants bind JAG1 [Homo sapiens]
[Reaction:2768999] NOTCH1 PEST domain mutants bind JAG1 [Homo sapiens]
[Reaction:2900743] NOTCH1 HD+PEST domain mutants bind JAG1 [Homo sapiens]
[Reaction:9604247] JAG1 binds NOTCH4 [Homo sapiens]
[Reaction:9980904] JAG1 (stalk cell) binds Fringe-modified NOTCH1 (tip cell) [Homo sapiens]
(output)[BlackBoxEvent:8878212] JAG1 gene expression is inhibited by RUNX3 [Homo sapiens]
[BlackBoxEvent:9832187] Expression of JAG1 during nephron development [Homo sapiens]
(physicalEntity)[PhysicalEntityCellType:9980911] JAG1 [plasma membrane] in endothelial stalk cell
(updatedInstance)[_UpdateTracker:9866706] Update Tracker - [EntityWithAccessionedSequence:157098] JAG1 [plasma membrane] - v25:[modifyName]
[_UpdateTracker:9871324] Update Tracker - [EntityWithAccessionedSequence:157098] JAG1 [plasma membrane] - v39:[addName]
[_UpdateTracker:9871673] Update Tracker - [EntityWithAccessionedSequence:157098] JAG1 [plasma membrane] - v40:[modifyEndCoordinate, modifyStartCoordinate]
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No pathways have been reviewed or authored by JAG1 [plasma membrane] (157098)
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