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Details on Person Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation

Class:Id	Reaction:156808
_displayName	Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation
_doRelease	TRUE
_timestamp	2017-05-16 15:40:22
authored	[InstanceEdit:156811] Matthews, L, 2004-12-13 00:33:09
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:157315] Gebauer, F, 2004-12-20 00:00:00
edited	[InstanceEdit:165113] Matthews, L, 0000-00-00 00:00:00
input	[Complex:72571] 43S complex [cytosol] [Homo sapiens] [Complex:156809] Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:72557] EIF1AX [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:156803] PABPC1 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:157289] A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation
modified	[InstanceEdit:156819] Matthews, L, 2004-12-13 00:44:57 [InstanceEdit:156837] Matthews, L, 2004-12-13 00:59:20 [InstanceEdit:156896] Matthews, L, 2004-12-14 14:20:02 [InstanceEdit:156897] Matthews, L, 2004-12-14 14:21:35 [InstanceEdit:156938] Matthews, L, 2004-12-14 20:57:48 [InstanceEdit:157303] Matthews, L, 2004-12-20 12:35:16 [InstanceEdit:157321] Matthews, L, 2004-12-21 00:15:51 [InstanceEdit:157806] Matthews, L, 2005-01-07 14:12:16 [InstanceEdit:157850] Matthews, L, 2005-01-07 22:43:47 [InstanceEdit:157984] Matthews, L, 2005-01-11 20:36:26 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9006434] Jupe, Steve, 2017-05-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation
output	[Complex:156804] 43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:72557] EIF1AX [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:72647] Cap-bound mRNA is activated by helicases [Homo sapiens] [Reaction:72635] eIF4F binds to mRNP [Homo sapiens]
releaseDate	2005-02-01
requiredInputComponent	[EntityWithAccessionedSequence:156803] PABPC1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:72584] EIF4G1 [cytosol] [Homo sapiens]
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358754] R-HSA-156808.4
summation	[Summation:156813] The precise order of events leading to the circularization o...
(hasEvent)	[Pathway:72649] Translation initiation complex formation [Homo sapiens]
(precedingEvent)	[Reaction:156823] Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA [Homo sapiens]
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