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Details on Person MMP1 can degrade fibronectin (Fukai et al. 1995), as can MMP...

Class:Id	Summation:1566944
_displayName	MMP1 can degrade fibronectin (Fukai et al. 1995), as can MMP...
_timestamp	2013-07-04 14:29:05
created	[InstanceEdit:1566968] Jupe, S, 2011-09-06
literatureReference	[LiteratureReference:1566943] Release of biological activities from quiescent fibronectin by a conformational change and limited proteolysis by matrix metalloproteinases [LiteratureReference:1566949] Purification of the neutral proteoglycan-degrading metalloproteinase from human articular cartilage tissue and its identification as stromelysin matrix metalloproteinase-3 [LiteratureReference:1474211] Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases [LiteratureReference:1566955] Matrix metalloproteinase-3 (stromelysin-1). Identification as the cartilage acid metalloprotease and effect of pH on catalytic properties and calcium affinity [LiteratureReference:1566956] Pump-1 cDNA codes for a protein with characteristics similar to those of classical collagenase family members [LiteratureReference:1564071] Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line [LiteratureReference:1566966] Degradation of fibronectin fibrils by matrilysin and characterization of the degradation products [LiteratureReference:1566947] Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase [LiteratureReference:1564199] The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction [LiteratureReference:2485117] MT1-MMP regulates the turnover and endocytosis of extracellular matrix fibronectin [LiteratureReference:2514832] Cathepsin s promotes human preadipocyte differentiation: possible involvement of fibronectin degradation [LiteratureReference:2485114] Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions [LiteratureReference:2533919] The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces [LiteratureReference:2533832] Fibronectin matrix turnover occurs through a caveolin-1-dependent process
modified	[InstanceEdit:2485082] Jupe, S, 2012-09-28 [InstanceEdit:2514825] Jupe, S, 2012-10-10 [InstanceEdit:2533918] Jupe, S, 2012-10-22 [InstanceEdit:2984194] Jupe, S, 2013-01-15 [InstanceEdit:3787960] Jupe, S, 2013-07-04
text	MMP1 can degrade fibronectin (Fukai et al. 1995), as can MMP3 (Gunja-Smith et al. 1985, Nicholson et al. 1989, Wilhelm et al. 1993, Fukai et al. 1995), MMP7 (Quantin et al. 1989, Miyazaki et al. 1990, Fukai et al. 1995, von Bredow et al. 1995), MMP10 (Nicholson et al. 1989), MMP12 (Gronski et al. 1997), MMP13 (Knauper et al. 1997), MMP14 (Shi & Sottile 2011) and 19 (Stracke et al. 2000). Cathepsin S is able to degrade fibronectin (Taleb et al. 2006). Studies have shown that fibronectin turnover is not prevented by protease inhibitors (Sottile & Hocking 2002) suggesting that caveolin-1-mediated endocytosis and intracellular degradation are involved (Salicioni et al. 2002, Sottile & Chandler 2004).
(summation)	[Reaction:1566981] Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS [Homo sapiens]
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