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Details on Person M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

Class:IdLiteratureReference:156676
_displayNameM-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP
_timestamp2005-06-16 20:42:48
author[Person:77569] Watanabe, Nobumoto
[Person:156681] Arai, H
[Person:156717] Nishihara, Y
[Person:156703] Taniguchi, M
[Person:164740] Watanabe, N
[Person:68384] Hunter, Tony
[Person:156688] Osada, H
created[InstanceEdit:156670] Gillespie, ME, 2004-12-09 02:18:13
journalProc Natl Acad Sci U S A
modified[InstanceEdit:164741] Gopinathrao, G, 2005-06-16 20:42:48
pages4419-24
pubMedIdentifier15070733
titleM-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP
volume101
year2004
(literatureReference)[Reaction:156699] Inactivation of Wee1 kinase [Homo sapiens]
[Pathway:156711] Polo-like kinase mediated events [Homo sapiens]
[Reaction:349481] Phosphorylation of Wee1 on S123 during interphase [Homo sapiens]
[Reaction:349485] Association of Plk1 with phospho- S123, S121 Wee1A [Homo sapiens]
[Reaction:349580] Association of Wee1A with beta-TrCP1/2 [Homo sapiens]
[Reaction:349587] Proteasome mediated degradation of Wee1A [Homo sapiens]
[Summation:349480] At the onset of M phase, when Plk1 accumulates and is activa...
[Summation:349582] Phosphorylation of Wee1A on S123 during interphase appears ...
[Summation:349584] Ubiquitinated Wee1A is degraded by the proteasome ( Wantanab...
[Summation:349590] Phosphorylation of Wee1 on S123 during interphase may be me...
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