Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:F1NSM7 Unknown
| Class:Id | ReferenceGeneProduct:1551969 |
|---|---|
| _chainChangeLog | signal peptide:1-18 added on Fri February 6 2015;chain:19-743 added on Fri February 6 2015 |
| _displayName | UniProt:F1NSM7 Unknown |
| _timestamp | 2023-11-03 18:39:20 |
| chain | signal peptide:1-18 chain:19-743 |
| checksum | 04F012A6D0E9D046 |
| comment | FUNCTION Major component of the eggshell matrix. May play an important role in the regulation of calcite growth during eggshell calcification. May also regulate the mineralization process in developing and growing bones.SUBCELLULAR LOCATION Synthesized and secreted by the granular epithelial cells of the uterus and incorporated into the eggshell matrix.TISSUE SPECIFICITY In the eggshell, expressed mainly in the palisade and mammillary layers. Expression also detected in the hypertrophic zone of the epiphyseal growth plate, and in cortical and medullary bone (at protein level). Highly expressed in uterus. Not detected in the proximal oviduct, liver, magnum, duodenum and kidney.DEVELOPMENTAL STAGE Expressed at high levels at the middle of the calcification stage of shell formation. Expression levels are similar at 3-4 hours post-oviposition prior to entry of the egg into the uterus and at 16-17 hours post-oviposition during eggshell calcification. Expressed in tibia from 5 dpc and in mandible from 7 dpc until the end of embryonic development at 19 dpc. Expression detected first in osteoblasts, in later stages both in osteoblasts and osteocytes, and by the end of embryonic development mainly in osteocytes.PTM Asn-62 is fully glycosylated, whereas only less than 10% of Asn-293 seem to be glycosylated.SIMILARITY Belongs to the osteoregulin family. |
| created | [InstanceEdit:1551960] Weiser, JD |
| description | recommendedName: fullName evidence="10"Ovocleidin-116 shortName evidence="8"OC-116 |
| identifier | F1NSM7 |
| isSequenceChanged | FALSE |
| keyword | Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Reference proteome Secreted Signal |
| modified | [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:5691543] Weiser, JD [InstanceEdit:6791590] Weiser, JD [InstanceEdit:6807888] Weiser, JD [InstanceEdit:8856987] Weiser, JD [InstanceEdit:8869714] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:8944791] Weiser, JD [InstanceEdit:8964659] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9750299] Weiser, JD [InstanceEdit:9819394] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | No name |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | OC116_CHICK Q9PUT1 |
| sequenceLength | 743 |
| species | [Species:49591] Gallus gallus |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:F1NSM7 Unknown (1551969)
