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Details on Person Ferrous iron reduces the BH3 radical back to BH4

Class:Id	Reaction:1497883
_displayName	Ferrous iron reduces the BH3 radical back to BH4
_doRelease	TRUE
_timestamp	2017-10-16 13:46:11
authored	[InstanceEdit:1497960] Jassal, B, 2011-08-17
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1497774] Jassal, B, 2011-08-17
edited	[InstanceEdit:1497960] Jassal, B, 2011-08-17
input	[SimpleEntity:71067] Fe2+ [cytosol] [SimpleEntity:1497797] BH3. [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1497844] Redox function of tetrahydrobiopterin and effect of L-arginine on oxygen binding in endothelial nitric oxide synthase
modified	[InstanceEdit:1497959] Jassal, B, 2011-08-17 [InstanceEdit:1502546] Jassal, B, 2011-08-23 [InstanceEdit:9025985] D'Eustachio, Peter, 2017-10-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ferrous iron reduces the BH3 radical back to BH4
output	[SimpleEntity:29870] BH4 [cytosol] [SimpleEntity:111736] Fe3+ [cytosol]
precedingEvent	[Reaction:1497824] BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle [Homo sapiens] [Reaction:1475414] PTHP is reduced to BH4 by sepiapterin reductase (SPR) [Homo sapiens] [Reaction:1497855] Ascorbate can reduce the BH3 radical back to BH4 [Homo sapiens] [Reaction:1497883] Ferrous iron reduces the BH3 radical back to BH4 [Homo sapiens]
releaseDate	2011-09-20
reviewed	[InstanceEdit:1502545] D'Eustachio, P, 2011-08-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1591341] R-HSA-1497883.3
summation	[Summation:1497859] Heme iron from the oxygenase domain of eNOS can reduce the B...
(hasEvent)	[Pathway:1474151] Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation [Homo sapiens]
(precedingEvent)	[Reaction:1475414] PTHP is reduced to BH4 by sepiapterin reductase (SPR) [Homo sapiens] [Reaction:1497824] BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle [Homo sapiens] [Reaction:1497866] Peroxynitrite can oxidise BH4 to the BH3 radical [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9780387] Update Tracker - [Reaction:1497883] Ferrous iron reduces the BH3 radical back to BH4 - v63:[add_removeOutput]
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No pathways have been reviewed or authored by Ferrous iron reduces the BH3 radical back to BH4 (1497883)