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Details on Person PA is converted to CDP-DAG by CDS2

Class:Id	Reaction:1483165
_displayName	PA is converted to CDP-DAG by CDS2
_doRelease	TRUE
_timestamp	2012-05-31 09:44:07
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524097] phosphatidate cytidylyltransferase activity of CDS2 [mitochondrial inner membrane]
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:1524101] PA [mitochondrial inner membrane] [SimpleEntity:110577] CTP [mitochondrial matrix]
isChimeric	FALSE
literatureReference	[LiteratureReference:1482952] The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content [LiteratureReference:1483032] Cardiolipin is synthesized on the matrix side of the inner membrane in rat liver mitochondria [LiteratureReference:1483143] Participation of the microsomal CDP-diglycerides in the mitochondrial biosynthesis of phosphatidylglycerol
modified	[InstanceEdit:1491769] Williams, MG, 2011-08-15 [InstanceEdit:1524094] Williams, MG, 2011-08-24 [InstanceEdit:1602449] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PA is converted to CDP-DAG by CDS2
output	[SimpleEntity:1524064] CDP-DAG [mitochondrial inner membrane] [SimpleEntity:159450] PPi [mitochondrial matrix]
precedingEvent	[Reaction:1483099] PA translocates from the outer to the inner mitochondrial membrane [Homo sapiens] [Reaction:1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) [Homo sapiens] [Reaction:8954398] PLD6 dimer hydrolyses cardiolipin to PA and PG [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294908] R-HSA-1483165.2
summation	[Summation:1482942] At the inner mitochondrial (IM) membrane, phosphatidate cyti...
(hasEvent)	[Pathway:1483148] Synthesis of PG [Homo sapiens]
(precedingEvent)	[Reaction:1482939] CDP-DAG is converted to PGP by PGS1 [Homo sapiens] [Reaction:1483063] PG and CDP-DAG are converted to CL by CRLS1 [Homo sapiens]
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No pathways have been reviewed or authored by PA is converted to CDP-DAG by CDS2 (1483165)