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Details on Person PC is transphosphatidylated to PG by PLD1-4/6

Class:Id	Reaction:1483142
_displayName	PC is transphosphatidylated to PG by PLD1-4/6
_doRelease	TRUE
_timestamp	2012-05-31 09:54:01
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524118] D-type glycerophospholipase activity of PLD1-4/6 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
inferredFrom	[Reaction:1483172] PC is transphosphatidylated to PG by Pld1-4/6 [Mus musculus]
input	[SimpleEntity:426925] PC [endoplasmic reticulum membrane] [SimpleEntity:76116] Glycerol [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1483192] Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family [LiteratureReference:1602044] Characterization of human PLD2 and the analysis of PLD isoform splice variants [LiteratureReference:1602052] A human homolog of the vaccinia virus HindIII K4L gene is a member of the phospholipase D superfamily
modified	[InstanceEdit:1491769] Williams, MG, 2011-08-15 [InstanceEdit:1524116] Williams, MG, 2011-08-24 [InstanceEdit:1556360] Williams, MG, 2011-09-05 [InstanceEdit:1602054] Williams, MG, 2011-09-13 [InstanceEdit:1602450] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PC is transphosphatidylated to PG by PLD1-4/6
output	[SimpleEntity:1483256] PG [endoplasmic reticulum membrane] [SimpleEntity:264618] Cho [cytosol]
precedingEvent	[Reaction:1483219] PC is exchanged with PI by PITPNB [Homo sapiens] [Reaction:1483211] PC:PITPNB is transported from the Golgi membrane to the ER membrane [Homo sapiens] [Reaction:1482976] CDP-DAG is converted to PI by CDIPT [Homo sapiens] [Reaction:1482598] 1-acyl LPI is acylated to PI by MBOAT7 [Homo sapiens] [Reaction:1482626] 2-acyl LPI is acylated to PI by MBOAT7 [Homo sapiens] [Reaction:1676124] PI4P is dephosphorylated to PI by SACM1L at the ER membrane [Homo sapiens] [Reaction:1482961] CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane [Homo sapiens] [Reaction:1483081] PCho and CTP are condensed to CDP-Cho by PCYT1 dimer [Homo sapiens] [Reaction:1483203] PA is dephosphorylated to DAG by LPIN [Homo sapiens] [Reaction:1482777] TAG is hydrolyzed to DAG by PNPLA2/3 [Homo sapiens] [Reaction:1482654] 2-MAG is transacylated to DAG by PNPLA2/3 [Homo sapiens] [Reaction:1482547] 1-acyl LPC is acylated to PC by LPCAT [Homo sapiens] [Reaction:1482856] PC is hydrolyzed to 1-acyl LPC by PLA2[5] [Homo sapiens] [Reaction:1482816] PC is hydrolyzed to 1-acyl LPC by PLA2[6] [Homo sapiens] [Reaction:1482533] 2-acyl LPC is acylated to PC by LPCAT [Homo sapiens] [Reaction:1482862] PC is hydrolysed to 2-acyl LPC by PLA2[7] [Homo sapiens] [Reaction:1482827] PC is hydrolyzed to 2-acyl LPC by PLA2G4C [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295302] R-HSA-1483142.2
summation	[Summation:1483073] In the endoplasmic reticulum (ER) membrane, phospholipase D1...
(hasEvent)	[Pathway:1483148] Synthesis of PG [Homo sapiens]
(precedingEvent)	[Reaction:1482900] PG is hydrolyzed to 1-acyl LPG by PLA2[1] [Homo sapiens] [Reaction:1482907] PG is hydrolyzed to 1-acyl LPG by PLA2G2A [Homo sapiens] [Reaction:1482920] PG is hydrolyzed to 2-acyl LPG by PLA2[14] [Homo sapiens] [Reaction:1483218] PG transports from the ER membrane to the late endosome membrane [Homo sapiens]
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No pathways have been reviewed or authored by PC is transphosphatidylated to PG by PLD1-4/6 (1483142)