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Details on Person PI is exchanged with PC by PITPNB
Class:Id Reaction:1483087
_displayName PI is exchanged with PC by PITPNB
_doRelease TRUE
_timestamp 2024-02-12 20:11:02
authored [InstanceEdit:1678579] Williams, MG, 2011-10-18
catalystActivity [CatalystActivity:9855947] phosphatidylcholine transfer activity of PI:PITPNB [Golgi membrane]
catalystActivityReference [CatalystActivityReference:9855946] phosphatidylcholine transfer activity of PI:PITPNB [Golgi membrane] Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine
compartment [Compartment:20699] Golgi membrane
created [InstanceEdit:1483214] Williams, MG, 2011-08-12
edited [InstanceEdit:1482514] Williams, MG, 2011-08-12
input [Complex:1524150] PI:PITPNB [Golgi membrane] [Homo sapiens] [SimpleEntity:429785] PC [Golgi membrane]
isChimeric FALSE
literatureReference [LiteratureReference:1483105] Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells [LiteratureReference:1483109] Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum [LiteratureReference:1483200] Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine [LiteratureReference:1483223] Structure of PITPbeta in complex with phosphatidylcholine: comparison of structure and lipid transfer to other PITP isoforms [LiteratureReference:1483130] Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association [LiteratureReference:1483188] Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol
modified [InstanceEdit:1493096] Williams, MG, 2011-08-15 [InstanceEdit:1524147] Williams, MG, 2011-08-24 [InstanceEdit:1602491] Williams, MG, 2011-09-14 [InstanceEdit:1678578] Williams, MG, 2011-10-18 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2247961] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9855942] D'Eustachio, Peter, 2023-12-08 [InstanceEdit:9860911] D'Eustachio, Peter, 2024-02-12
name PI is exchanged with PC by PITPNB
output [SimpleEntity:1524146] PI [Golgi membrane] [Complex:1524122] PC:PITPNB [Golgi membrane] [Homo sapiens]
precedingEvent
previousReviewStatus [ReviewStatus:9821384] two stars
releaseDate 2012-06-12
reviewed [InstanceEdit:2247963] Wakelam, Michael, 2012-05-14 [InstanceEdit:9860910] Hill, David P, 2024-02-12
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:2295131] R-HSA-1483087.3
structureModified [InstanceEdit:9855942] D'Eustachio, Peter, 2023-12-08
summation [Summation:1482877] At the Golgi membrane, phosphatidylinositol (PI) is exchange...
(hasEvent) [Pathway:1483196] PI and PC transport between ER and Golgi membranes [Homo sapiens]
(precedingEvent) [Reaction:1483211] PC:PITPNB is transported from the Golgi membrane to the ER membrane [Homo sapiens] [Reaction:1675883] PI is phosphorylated to PI4P by PI4KB at the Golgi membrane [Homo sapiens] [Reaction:1675961] PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane [Homo sapiens] [Reaction:1676185] PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane [Homo sapiens]
(updatedInstance) [_UpdateTracker:9864048] Update Tracker - [Reaction:1483087] PI is exchanged with PC by PITPNB - v88:[addCatalystActivity, modifyText]
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