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Details on Person PG and CDP-DAG are converted to CL by CRLS1

Class:Id	Reaction:1483063
_displayName	PG and CDP-DAG are converted to CL by CRLS1
_doRelease	TRUE
_timestamp	2012-05-31 09:52:29
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524138] cardiolipin synthase (CMP-forming) activity of CRLS1 [mitochondrial inner membrane]
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:1524042] PG [mitochondrial inner membrane] [SimpleEntity:1524064] CDP-DAG [mitochondrial inner membrane]
isChimeric	FALSE
literatureReference	[LiteratureReference:1483103] Identification and characterization of human cardiolipin synthase [LiteratureReference:1483026] Cloning and characterization of a cDNA encoding human cardiolipin synthase (hCLS1)
modified	[InstanceEdit:1491770] Williams, MG, 2011-08-15 [InstanceEdit:1524131] Williams, MG, 2011-08-24 [InstanceEdit:1602490] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PG and CDP-DAG are converted to CL by CRLS1
output	[SimpleEntity:1524072] cardiolipin [mitochondrial inner membrane] [SimpleEntity:1524067] CMP [mitochondrial matrix]
precedingEvent	[Reaction:1483197] PTPMT1 dephosphorylates PGP to PG [Homo sapiens] [Reaction:1482939] CDP-DAG is converted to PGP by PGS1 [Homo sapiens] [Reaction:1483165] PA is converted to CDP-DAG by CDS2 [Homo sapiens] [Reaction:1483099] PA translocates from the outer to the inner mitochondrial membrane [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295230] R-HSA-1483063.2
summation	[Summation:1482965] At the inner mitochondrial membrane (IM), cardiolipin syntha...
(hasEvent)	[Pathway:1483076] Synthesis of CL [Homo sapiens]
(precedingEvent)	[Reaction:1482778] CL is hydrolyzed to MLCL by PLA2G6 (IM) [Homo sapiens] [Reaction:1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) [Homo sapiens]
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No pathways have been reviewed or authored by PG and CDP-DAG are converted to CL by CRLS1 (1483063)