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Details on Person CDP-DAG is converted to PI by CDIPT

Class:Id	Reaction:1482976
_displayName	CDP-DAG is converted to PI by CDIPT
_doRelease	TRUE
_timestamp	2012-05-31 09:45:13
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524066] CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity of CDIPT:Mg2+/Mn2+ [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482967] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:426955] CDP-DAG [endoplasmic reticulum membrane] [SimpleEntity:426910] Ins [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1482952] The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content
modified	[InstanceEdit:1491768] Williams, MG, 2011-08-15 [InstanceEdit:1524062] Williams, MG, 2011-08-24 [InstanceEdit:1602443] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CDP-DAG is converted to PI by CDIPT
output	[SimpleEntity:426639] PI [endoplasmic reticulum membrane] [SimpleEntity:109395] CMP [cytosol]
precedingEvent	[Reaction:1483121] PA is converted to CDP-DAG by CDS1 [Homo sapiens] [Reaction:75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) [Homo sapiens] [Reaction:1483182] PC is hydrolyzed to PA and choline by PLD1/2 [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294959] R-HSA-1482976.2
summation	[Summation:1482881] At the endoplasmic reticulum (ER) membrane, CDP-diacylglycer...
(hasEvent)	[Pathway:1483226] Synthesis of PI [Homo sapiens]
(precedingEvent)	[Reaction:1482825] PI is hydrolyzed to 1-acyl LPI by PLA2[11] [Homo sapiens] [Reaction:1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] [Homo sapiens] [Reaction:1482932] PI is hydrolyzed to 2-acyl LPI by PLA2[13] [Homo sapiens] [Reaction:1483219] PC is exchanged with PI by PITPNB [Homo sapiens] [Reaction:1675813] PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane [Homo sapiens]
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No pathways have been reviewed or authored by CDP-DAG is converted to PI by CDIPT (1482976)