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Details on Person CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane

Class:Id	Reaction:1482973
_displayName	CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane
_doRelease	TRUE
_timestamp	2012-05-31 09:39:39
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524061] diacylglycerol cholinephosphotransferase activity of CHPT1:Mg2+/Mn2+ [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482967] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:1524060] CDP-Cho [cytosol] [SimpleEntity:1524057] DAG [Golgi membrane]
isChimeric	FALSE
literatureReference	[LiteratureReference:1482959] Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine [LiteratureReference:1482937] Cloning, genomic organization, and characterization of a human cholinephosphotransferase [LiteratureReference:1482954] PC and PE synthesis: mixed micellar analysis of the cholinephosphotransferase and ethanolaminephosphotransferase activities of human choline/ethanolamine phosphotransferase 1 (CEPT1) [LiteratureReference:1482958] The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity
modified	[InstanceEdit:1491768] Williams, MG, 2011-08-15 [InstanceEdit:1524062] Williams, MG, 2011-08-24 [InstanceEdit:1524171] Williams, MG, 2011-08-24 [InstanceEdit:1602443] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane
output	[SimpleEntity:109395] CMP [cytosol] [SimpleEntity:429785] PC [Golgi membrane]
precedingEvent	[Reaction:1483081] PCho and CTP are condensed to CDP-Cho by PCYT1 dimer [Homo sapiens] [Reaction:1483004] Cho is phosphorylated to PCho by CHK dimer [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294734] R-HSA-1482973.2
summation	[Summation:1482879] At the Golgi membrane, cholinephosphotransferase 1 (CHPT1) c...
(hasEvent)	[Pathway:1483191] Synthesis of PC [Homo sapiens]
(precedingEvent)	[Reaction:1483087] PI is exchanged with PC by PITPNB [Homo sapiens]
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No pathways have been reviewed or authored by CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (1482973)