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Details on Person PI is hydrolyzed to 2-acyl LPI by PLA2[13]

Class:Id	Reaction:1482932
_displayName	PI is hydrolyzed to 2-acyl LPI by PLA2[13]
_doRelease	TRUE
_timestamp	2012-05-31 09:46:12
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524140] glycerophospholipid phospholipase A1 activity of PLA2(13) [cytosol]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482800] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:426639] PI [endoplasmic reticulum membrane] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1482664] Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms
modified	[InstanceEdit:1493096] Williams, MG, 2011-08-15 [InstanceEdit:1524147] Williams, MG, 2011-08-24 [InstanceEdit:1602491] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:1979630] Williams, MG, 2011-11-08 [InstanceEdit:2230935] D'Eustachio, P, 2012-05-05 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PI is hydrolyzed to 2-acyl LPI by PLA2[13]
output	[SimpleEntity:1498737] 2-acyl LPI [endoplasmic reticulum membrane] [SimpleEntity:1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent	[Reaction:1482976] CDP-DAG is converted to PI by CDIPT [Homo sapiens] [Reaction:1483121] PA is converted to CDP-DAG by CDS1 [Homo sapiens] [Reaction:1482598] 1-acyl LPI is acylated to PI by MBOAT7 [Homo sapiens] [Reaction:1482825] PI is hydrolyzed to 1-acyl LPI by PLA2[11] [Homo sapiens] [Reaction:1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] [Homo sapiens] [Reaction:1482626] 2-acyl LPI is acylated to PI by MBOAT7 [Homo sapiens] [Reaction:1482932] PI is hydrolyzed to 2-acyl LPI by PLA2[13] [Homo sapiens] [Reaction:1676124] PI4P is dephosphorylated to PI by SACM1L at the ER membrane [Homo sapiens] [Reaction:1675813] PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane [Homo sapiens] [Reaction:8867667] OSBPs transport 25OH-CHOL from ER membrane to plasma membrane [Homo sapiens] [Reaction:8868402] OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane [Homo sapiens] [Reaction:8867876] OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294993] R-HSA-1482932.2
summation	[Summation:1482770] At the endoplasmic reticulum (ER) membrane, phosphatidylinos...
(hasEvent)	[Pathway:1482922] Acyl chain remodelling of PI [Homo sapiens]
(precedingEvent)	[Reaction:1482626] 2-acyl LPI is acylated to PI by MBOAT7 [Homo sapiens]
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No pathways have been reviewed or authored by PI is hydrolyzed to 2-acyl LPI by PLA2[13] (1482932)