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Details on Person PE is hydrolyzed to 2-acyl LPE by PLA2G4C

Class:Id	Reaction:1482892
_displayName	PE is hydrolyzed to 2-acyl LPE by PLA2G4C
_doRelease	TRUE
_timestamp	2012-05-31 09:45:35
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524121] glycerophospholipid phospholipase A1 activity of PLA2G4C [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482800] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:1500581] PE [endoplasmic reticulum membrane] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1482664] Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms [LiteratureReference:1482631] Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2gamma) [LiteratureReference:1482624] Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma)
modified	[InstanceEdit:1484771] Williams, MG, 2011-08-12 [InstanceEdit:1491770] Williams, MG, 2011-08-15 [InstanceEdit:1524131] Williams, MG, 2011-08-24 [InstanceEdit:1602490] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2230933] D'Eustachio, P, 2012-05-05 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PE is hydrolyzed to 2-acyl LPE by PLA2G4C
output	[SimpleEntity:1498729] 2-acyl LPE [endoplasmic reticulum membrane] [SimpleEntity:1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent	[Reaction:1483077] PE transports from the mitochondrial membrane to the ER [Homo sapiens] [Reaction:1483212] PS is decarboxylated to PE by PISD [Homo sapiens] [Reaction:1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482667] 1-acyl LPE is acylated to PE by LPEAT [Homo sapiens] [Reaction:1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] [Homo sapiens] [Reaction:1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3] [Homo sapiens] [Reaction:1482646] 2-acyl LPE is acylated to PE by LPEAT [Homo sapiens] [Reaction:1482828] PE is hydrolyzed to 2-acyl LPE by PLA2[4] [Homo sapiens] [Reaction:1482892] PE is hydrolyzed to 2-acyl LPE by PLA2G4C [Homo sapiens] [Reaction:1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 [Homo sapiens] [Reaction:1483190] PETA and CTP are condensed to CDP-ETA by PCY2 [Homo sapiens] [Reaction:1483203] PA is dephosphorylated to DAG by LPIN [Homo sapiens] [Reaction:1482777] TAG is hydrolyzed to DAG by PNPLA2/3 [Homo sapiens] [Reaction:1482654] 2-MAG is transacylated to DAG by PNPLA2/3 [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294974] R-HSA-1482892.2
summation	[Summation:1482831] At the endoplasmic reticulum (ER) membrane, phosphatidyletha...
(hasEvent)	[Pathway:1482839] Acyl chain remodelling of PE [Homo sapiens]
(precedingEvent)	[Reaction:1482545] 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C [Homo sapiens] [Reaction:1482646] 2-acyl LPE is acylated to PE by LPEAT [Homo sapiens]
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No pathways have been reviewed or authored by PE is hydrolyzed to 2-acyl LPE by PLA2G4C (1482892)