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Details on Person MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)

Class:IdReaction:1482850
_displayNameMLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)
_doReleaseTRUE
_timestamp2017-05-10 21:06:14
authored[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity[CatalystActivity:1524093] acyltransferase activity, transferring groups other than amino-acyl groups of TAZ [mitochondrial inner membrane]
compartment[Compartment:70616] mitochondrial inner membrane
created[InstanceEdit:1482800] Williams, MG, 2011-08-12
edited[InstanceEdit:1482514] Williams, MG, 2011-08-12
input[SimpleEntity:1498773] MLCL [mitochondrial inner membrane]
[SimpleEntity:1524083] PE [mitochondrial inner membrane]
isChimericFALSE
literatureReference[LiteratureReference:1482930] Remodeling of cardiolipin by phospholipid transacylation
[LiteratureReference:1482743] The enzymatic function of tafazzin
[LiteratureReference:1482809] Formation of molecular species of mitochondrial cardiolipin. 1. A novel transacylation mechanism to shuttle fatty acids between sn-1 and sn-2 positions of multiple phospholipid species
modified[InstanceEdit:1491769] Williams, MG, 2011-08-15
[InstanceEdit:1524094] Williams, MG, 2011-08-24
[InstanceEdit:1602449] Williams, MG, 2011-09-14
[InstanceEdit:1967225] Williams, MG, 2011-11-04
[InstanceEdit:2248822] D'Eustachio, P, 2012-05-14
[InstanceEdit:9005902] D'Eustachio, Peter, 2017-05-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)
output[SimpleEntity:1524072] cardiolipin [mitochondrial inner membrane]
[SimpleEntity:1524089] 1-acyl LPE [mitochondrial inner membrane]
precedingEvent
releaseDate2012-06-12
reverseReaction
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2294829] R-HSA-1482850.3
summation[Summation:1482824] At the inner mitochondrial membrane (IM), tafazzin (TAZ) con...
(hasEvent)[Pathway:1482798] Acyl chain remodeling of CL [Homo sapiens]
(precedingEvent)[Reaction:1482778] CL is hydrolyzed to MLCL by PLA2G6 (IM) [Homo sapiens]
[Reaction:1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) [Homo sapiens]
[Reaction:1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) [Homo sapiens]
(reverseReaction)[Reaction:1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) [Homo sapiens]
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