Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person MLCL is hydrolyzed to DLCL by PLA2G4A (IM)

Class:Id	Reaction:1482759
_displayName	MLCL is hydrolyzed to DLCL by PLA2G4A (IM)
_doRelease	TRUE
_timestamp	2012-05-31 09:48:01
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524096] A2-type glycerophospholipase activity of PLA2G4A:Ca2+ [mitochondrial inner membrane]
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1482800] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:1498773] MLCL [mitochondrial inner membrane] [SimpleEntity:113521] H2O [mitochondrial matrix]
isChimeric	FALSE
literatureReference	[LiteratureReference:1482754] Cardiolipin hydrolysis by human phospholipases A2. The multiple enzymatic activities of human cytosolic phospholipase A2 [LiteratureReference:1482518] Serine 228 is essential for catalytic activities of 85-kDa cytosolic phospholipase A2
modified	[InstanceEdit:1491769] Williams, MG, 2011-08-15 [InstanceEdit:1524094] Williams, MG, 2011-08-24 [InstanceEdit:1602449] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2230935] D'Eustachio, P, 2012-05-05 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MLCL is hydrolyzed to DLCL by PLA2G4A (IM)
output	[SimpleEntity:1498753] DLCL [mitochondrial inner membrane] [SimpleEntity:1524085] LCFA(-) [mitochondrial inner membrane]
precedingEvent	[Reaction:1482778] CL is hydrolyzed to MLCL by PLA2G6 (IM) [Homo sapiens] [Reaction:1483063] PG and CDP-DAG are converted to CL by CRLS1 [Homo sapiens] [Reaction:1482781] MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482850] MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482775] MLCL is acylated to CL by HADH (IM) [Homo sapiens] [BlackBoxEvent:1482857] CL transports from the ER to the IM [Homo sapiens] [Reaction:1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482781] MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482850] MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482775] MLCL is acylated to CL by HADH (IM) [Homo sapiens] [BlackBoxEvent:1482857] CL transports from the ER to the IM [Homo sapiens] [Reaction:1483063] PG and CDP-DAG are converted to CL by CRLS1 [Homo sapiens] [Reaction:1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1483063] PG and CDP-DAG are converted to CL by CRLS1 [Homo sapiens] [Reaction:1482781] MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482850] MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) [Homo sapiens] [Reaction:1482775] MLCL is acylated to CL by HADH (IM) [Homo sapiens] [BlackBoxEvent:1482857] CL transports from the ER to the IM [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295067] R-HSA-1482759.2
summation	[Summation:1482869] At the inner mitochondrial membrane (IM), the phospholipase ...
(hasEvent)	[Pathway:1482798] Acyl chain remodeling of CL [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:1482860] DLCL transports from the IM to the ER [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (1482759)