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Details on Person 1-acyl LPA is acylated to PA by AGPAT5 (OM)

Class:Id	Reaction:1482548
_displayName	1-acyl LPA is acylated to PA by AGPAT5 (OM)
_doRelease	TRUE
_timestamp	2012-05-31 09:49:58
authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1500599] 1-acylglycerol-3-phosphate O-acyltransferase activity of AGPAT5 [mitochondrial outer membrane]
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482525] Williams, MG, 2011-08-12
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:1500580] 1-acyl LPA [mitochondrial outer membrane] [SimpleEntity:1500578] acyl-CoA [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1482520] Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria
modified	[InstanceEdit:1500602] Williams, MG, 2011-08-19 [InstanceEdit:1602344] Williams, MG, 2011-09-14 [InstanceEdit:1967225] Williams, MG, 2011-11-04 [InstanceEdit:2248822] D'Eustachio, P, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	1-acyl LPA is acylated to PA by AGPAT5 (OM)
output	[SimpleEntity:1500590] PA [mitochondrial outer membrane] [SimpleEntity:76194] CoA-SH [cytosol]
precedingEvent	[Reaction:1482695] G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) [Homo sapiens] [Reaction:1483107] GPETA is hydrolyzed to ETA and G3P by GPCPD1 [Homo sapiens] [Reaction:75889] DHAP is converted to G3P by GPD1/GPD1L [Homo sapiens] [Reaction:75887] Conversion of Glycerol to Glycerol-3-phosphate [Homo sapiens] [Reaction:1483116] GPCho is hydrolyzed to Cho and G3P by GPCPD1 [Homo sapiens] [Reaction:1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) [Homo sapiens] [Reaction:1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295145] R-HSA-1482548.2
summation	[Summation:1482651] At the outer mitochondrial (OM) membrane, 1-acyl lysophospha...
(hasEvent)	[Pathway:1483166] Synthesis of PA [Homo sapiens]
(precedingEvent)	[Reaction:1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) [Homo sapiens] [Reaction:1483099] PA translocates from the outer to the inner mitochondrial membrane [Homo sapiens] [Reaction:6801250] TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane [Homo sapiens]
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