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Details on Person UniProt:Q6GYQ0-3 RALGAPA1
| Class:Id | ReferenceIsoform:148204 |
|---|---|
| _chainChangeLog | chain:1-2036 added on Fri February 6 2015 |
| _displayName | UniProt:Q6GYQ0-3 RALGAPA1 |
| _timestamp | 2026-02-20 22:59:16 |
| chain | chain:1-2036 |
| checksum | 7ADF5487908C14CB |
| comment | FUNCTION Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.SUBUNIT Component of the heterodimeric RalGAP1 complex with RALGAPB. Heterodimerization is required for activity. Interacts with the HLH region of TCF3/isoform E12 (By similarity).INTERACTION Translocated to the nucleus, when associated with TCF3/E12.ALTERNATIVE PRODUCTS Widely expressed.DISEASE The disease is caused by variants affecting the gene represented in this entry. |
| created | [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10 |
| description | recommendedName: Ral GTPase-activating protein subunit alpha-1 alternativeName: GAP-related-interacting partner to E12 shortName: GRIPE alternativeName: GTPase-activating Rap/Ran-GAP domain-like 1 alternativeName: Tuberin-like protein 1 alternativeName: p240 |
| geneName | RALGAPA1 GARNL1 KIAA0884 TULIP1 |
| identifier | Q6GYQ0 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Coiled coil Cytoplasm Disease variant GTPase activation Nucleus Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | RALGAPA1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9000806] ENSEMBL:ENSG00000174373 RALGAPA1 [Homo sapiens] |
| secondaryIdentifier | RGPA1_HUMAN A6NMA4 B9EK38 C5NU19 O94960 Q6GYP9 Q6ZT23 Q86YF3 Q86YF5 Q8ND69 |
| sequenceLength | 2036 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q6GYQ0-3 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q6GYQ0-3 RALGAPA1 (148204)
