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Query author contributions in Reactome

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Details on Person UniProt:Q9C0E4 GRIP2

Class:IdReferenceGeneProduct:148195
_chainChangeLogchain:1-1043 added on Fri February 6 2015
_displayNameUniProt:Q9C0E4 GRIP2
_timestamp2026-02-20 22:10:29
chainchain:1-1043
checksum24686D50E5FB827F
commentFUNCTION May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.SUBUNIT Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR.INTERACTION PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4 (By similarity).MISCELLANEOUS Due to intron retention.SIMILARITY Belongs to the GRIP2 family.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Probable cloning artifact.
created[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
descriptionrecommendedName: fullName evidence="7"Glutamate receptor-interacting protein 2 shortName: GRIP-2
geneNameGRIP2
KIAA1719
identifierQ9C0E4
isSequenceChangedFALSE
keyword3D-structure
Alternative splicing
Cytoplasm
Membrane
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
nameGRIP2
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9607417] ENSEMBL:ENSG00000144596 GRIP2 [Homo sapiens]
secondaryIdentifierGRIP2_HUMAN
A0A087WU38
Q8TEH9
Q9H7H3
sequenceLength1043
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:148196] UniProt:Q9C0E4-2 GRIP2 [Homo sapiens]
[ReferenceIsoform:413611] UniProt:Q9C0E4-1 GRIP2 [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:416632] GRIP2 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:416643] GRIP2 [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q9C0E4 GRIP2 (148195)