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Details on Person UniProt:P49772-2 Flt3lg
| Class:Id | ReferenceIsoform:147353 |
|---|
| _chainChangeLog | signal peptide:1-26 added on Fri February 6 2015;chain:27-232 added on Fri February 6 2015 |
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| _displayName | UniProt:P49772-2 Flt3lg |
|---|
| _timestamp | 2025-02-21 19:48:01 |
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| chain | signal peptide:1-26
chain:27-232 |
|---|
| checksum | 3A3680D3CB69FBA6 |
|---|
| comment | FUNCTION Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. Essential for the development of natural killer (NK) cells, B cells, and dendritic cells (DCs).SUBUNIT Homodimer (soluble isoform).SUBCELLULAR LOCATION Biologically active.SUBCELLULAR LOCATION Inactive. |
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| description | recommendedName: Fms-related tyrosine kinase 3 ligand shortName: Flt3 ligand shortName: Flt3L alternativeName: SL cytokine |
|---|
| geneName | Flt3lg
Flt3l |
|---|
| identifier | P49772 |
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| isoformParent |
|
|---|
| isSequenceChanged | FALSE |
|---|
| keyword | Alternative splicing
Cell membrane
Cytokine
Disulfide bond
Glycoprotein
Membrane
Reference proteome
Secreted
Signal
Transmembrane
Transmembrane helix |
|---|
| modified | [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
|---|
| name | Flt3lg |
|---|
| referenceDatabase | [ReferenceDatabase:2] UniProt |
|---|
| secondaryIdentifier | FLT3L_MOUSE
Q64085 |
|---|
| sequenceLength | 232 |
|---|
| species | [Species:48892] Mus musculus |
|---|
| variantIdentifier | P49772-2 |
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No pathways have been reviewed or authored by UniProt:P49772-2 Flt3lg (147353)
