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Details on Person Beta defensin precursors are more simple in structure than t...
| Class:Id | Summation:1472839 |
|---|---|
| _displayName | Beta defensin precursors are more simple in structure than t... |
| _timestamp | 2011-11-04 16:48:22 |
| created | [InstanceEdit:1472846] Jupe, S, 2011-08-03 |
| literatureReference | [LiteratureReference:1472820] Defensins. Natural peptide antibiotics of human neutrophils [LiteratureReference:1973013] Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells [LiteratureReference:1973009] Detection of HBD1 peptide in peripheral blood mononuclear cell subpopulations by intracellular flow cytometry |
| modified | [InstanceEdit:1973019] Jupe, S, 2011-11-04 |
| text | Beta defensin precursors are more simple in structure than those of alpha defensins, having a signal sequence, a short or absent propiece and the mature defensin sequence at the C-terminus. The signal sequence is cleaved off by a signal peptidase in the endoplasmic reticulum (Ganz 2003). Mature beta defensins 1, 2, 3, and 4 are secreted primarily by epithelial cells but are also produced by some immune cells such as monocytes, macrophages and dendritic cells (Duits et al. 2000, Ryan et al. 2003). |
| (summation) | [Reaction:1471322] Beta-defensins are secreted [Homo sapiens] |
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No pathways have been reviewed or authored by Beta defensin precursors are more simple in structure than t... (1472839)
