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Details on Person HNP1-4 are stored in primary neutrophil granules

Class:Id	Reaction:1462003
_displayName	HNP1-4 are stored in primary neutrophil granules
_doRelease	TRUE
_timestamp	2016-11-30 21:35:56
authored	[InstanceEdit:1254178] Jupe, S, 2011-04-28
compartment	[Compartment:1470028] azurophil granule lumen [Compartment:17963] Golgi lumen
created	[InstanceEdit:1461974] Jupe, S, 2011-07-27
edited	[InstanceEdit:1461956] Jupe, S, 2011-07-27
input	[CandidateSet:1470042] Defensins alpha 1-4 [Golgi lumen] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1472820] Defensins. Natural peptide antibiotics of human neutrophils [LiteratureReference:1472834] Purification and characterization of human neutrophil peptide 4, a novel member of the defensin family
modified	[InstanceEdit:1470032] Jupe, S, 2011-08-01 [InstanceEdit:1471368] Jupe, S, 2011-08-03 [InstanceEdit:1472846] Jupe, S, 2011-08-03 [InstanceEdit:1966964] Jupe, S, 2011-11-04 [InstanceEdit:8949911] D'Eustachio, Peter, 2016-11-30 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	HNP1-4 are stored in primary neutrophil granules
output	[CandidateSet:1470049] Defensins alpha 1-4 [azurophil granule lumen] [Homo sapiens]
precedingEvent	[Reaction:1462039] Pro-HNP1-4 are cleaved to biologically active defensin [Homo sapiens] [BlackBoxEvent:1462023] Pre-pro-defensins are cleaved to remove the signal peptide [Homo sapiens]
releaseDate	2011-12-06
reviewed	[InstanceEdit:1966942] McDermott, AM, 2011-11-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2016149] R-HSA-1462003.3
summation	[Summation:1470040] Alpha defensins HNP1-4, the neutrophil defensins, are stored...
(hasEvent)	[Pathway:1462054] Alpha-defensins [Homo sapiens]
(precedingEvent)	[Reaction:1462041] HNP1-4 are released into phagocytic vacuoles [Homo sapiens]
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No pathways have been reviewed or authored by HNP1-4 are stored in primary neutrophil granules (1462003)