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Details on Person PIKfyve:ArPIKfyve:Sac3 [endosome membrane]

Class:Id	Complex:1460258
_displayName	PIKfyve:ArPIKfyve:Sac3 [endosome membrane]
_timestamp	2016-07-15 23:50:05
compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:1460249] May, B, 2011-07-26
hasComponent	[EntityWithAccessionedSequence:1460282] FIG4 [endosome membrane] [Homo sapiens] [EntityWithAccessionedSequence:1460260] Pikfyve [endosome membrane] [Mus musculus] [EntityWithAccessionedSequence:1460296] VAC14 [endosome membrane] [Homo sapiens]
isChimeric	TRUE
literatureReference	[LiteratureReference:1460276] ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality [LiteratureReference:1460267] Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes [LiteratureReference:1460254] PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	PIKfyve:ArPIKfyve:Sac3 Pikfyve:VAC14:FIG4
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:8911617] R-NUL-1460258.1
(inferredFrom)	[Complex:1460284] PIKFYVE:VAC14:FIG4 [endosome membrane] [Homo sapiens] [Complex:1460288] Pikfyve:Vac14:Fig4 [endosome membrane] [Mus musculus] [Complex:1460307] phospho-FAB1:VAC14:FIG4 [endosome membrane] [Homo sapiens] [Complex:1460319] phospho-Pikfyve:Vac14:Fig4 [cytosol] [Mus musculus]
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No pathways have been reviewed or authored by PIKfyve:ArPIKfyve:Sac3 [endosome membrane] (1460258)