Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person 14-3-3 binds p-5S,T642-AS160 (TBC1D4)

Class:Id	Reaction:1445149
_displayName	14-3-3 binds p-5S,T642-AS160 (TBC1D4)
_doRelease	TRUE
_timestamp	2017-11-20 04:21:07
authored	[InstanceEdit:1428498] May, B, 2011-07-07
compartment	[Compartment:437051] cytoplasmic vesicle membrane [Compartment:70101] cytosol
created	[InstanceEdit:1445147] May, B, 2011-07-12
edited	[InstanceEdit:1428498] May, B, 2011-07-07
inferredFrom	[Reaction:1445145] 14-3-3 Binds Phosphorylated Tbc1d4 (AS160) [Mus musculus]
input	[DefinedSet:1445138] 14-3-3 dimer [cytosol] [Homo sapiens] [Complex:1445133] p-5S,T642-AS160:IRAP [cytoplasmic vesicle membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1445022] A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160 [LiteratureReference:1445048] AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane [LiteratureReference:1445054] Reduced phosphorylation of AS160 contributes to glucocorticoid-mediated inhibition of glucose uptake in human and murine adipocytes [LiteratureReference:1445042] Resistance exercise and insulin regulate AS160 and interaction with 14-3-3 in human skeletal muscle [LiteratureReference:1454667] Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle
modified	[InstanceEdit:1454712] May, B, 2011-07-17 [InstanceEdit:1458495] May, B, 2011-07-21 [InstanceEdit:1977302] May, B, 2011-11-08 [InstanceEdit:2010555] May, B, 2011-11-22 [InstanceEdit:2108991] May, B, 2012-02-12 [InstanceEdit:2143453] May, B, 2012-02-26 [InstanceEdit:2255340] May, B, 2012-05-19 [InstanceEdit:2263482] May, B, 2012-05-21 [InstanceEdit:2428915] May, B, 2012-08-08 [InstanceEdit:2454134] May, B, 2012-08-21 [InstanceEdit:5252546] May, B, 2014-02-05 [InstanceEdit:9029483] May, Bruce, 2017-11-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	14-3-3 binds p-5S,T642-AS160 (TBC1D4)
output	[Complex:1445124] p-5S,T642-AS160:14-3-3:IRAP [cytoplasmic vesicle membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:1445144] p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4) [Homo sapiens] [Reaction:109702] PDPK1 phosphorylates AKT2 [Homo sapiens]
releaseDate	2012-09-18
reviewed	[InstanceEdit:2454132] Klip, Amira, 2012-08-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2464830] R-HSA-1445149.3
summation	[Summation:1458484] AS160 (TBC1D4) phosphorylated on serines 318, 341, 570, 588,...
(hasEvent)	[Pathway:1445148] Translocation of SLC2A4 (GLUT4) to the plasma membrane [Homo sapiens]
(precedingEvent)	[Reaction:2255343] RAB8A,10,13,14 exchange GDP for GTP [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787152] Update Tracker - [Reaction:1445149] 14-3-3 binds p-5S,T642-AS160 (TBC1D4) - v46:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by 14-3-3 binds p-5S,T642-AS160 (TBC1D4) (1445149)