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Details on Person PAOX:FAD oxidises NASPN to SPM

Class:IdReaction:141351
_displayNamePAOX:FAD oxidises NASPN to SPM
_doReleaseTRUE
_timestamp2025-06-10 22:54:12
authored[InstanceEdit:351144] Gopinathrao, G, 2008-05-21 15:52:50
catalystActivity[CatalystActivity:141347] N(1)-acetylpolyamine oxidase activity of PAOX:FAD [peroxisomal matrix]
compartment[Compartment:17951] peroxisomal matrix
created[InstanceEdit:141321] Jassal, B, 2004-09-16 09:57:59
crossReference[DatabaseIdentifier:9955556] RHEA:25801
edited[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
input[SimpleEntity:141323] NASPN [peroxisomal matrix]
[SimpleEntity:141343] H2O [peroxisomal matrix]
[SimpleEntity:113535] O2 [peroxisomal matrix]
literatureReference[LiteratureReference:266172] Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion
modified[InstanceEdit:141702] Jassal, B, 2004-09-30 09:25:15
[InstanceEdit:143491] Jassal, B, 2004-11-11 07:54:29
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:194325] Jassal, B, 2007-03-13 15:29:38
[InstanceEdit:266179] Jassal, B, 2008-04-25 13:27:59
[InstanceEdit:350661] Jassal, Bijay, 2008-05-20
[InstanceEdit:351778] Jassal, Bijay, 2008-05-28
[InstanceEdit:352324] Jassal, B, 2008-06-02 12:56:30
[InstanceEdit:353581] Gopinathrao, G, 2008-06-12 17:22:59
[InstanceEdit:354047] Gopinathrao, G, 2008-06-16 14:42:34
[InstanceEdit:377478] Gopinathrao, G, 2008-09-12 14:46:32
[InstanceEdit:377671] Gopinathrao, G, 2008-09-15 23:37:39
[InstanceEdit:5603083] Jassal, Bijay, 2014-06-27
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9955584] D'Eustachio, Peter, 2025-06-10
namePAOX:FAD oxidises NASPN to SPM
N(1)-acetylspermine + O2 + H2O => 3-acetamidopropanal + spermidine + H2O2
output[SimpleEntity:141324] SPM [peroxisomal matrix]
[SimpleEntity:113575] H2O2 [peroxisomal matrix]
[SimpleEntity:141327] 3AAPNAL [peroxisomal matrix]
precedingEvent
releaseDate2008-09-30
reviewed[InstanceEdit:377465] D'Eustachio, P, 2008-06-12 14:43:38
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5602271] Jassal, Bijay, 2014-06-23
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361706] R-HSA-141351.3
summation[Summation:178962] Acetylated spermine (NASPN) is oxidised by the flavoenzyme p...
(hasEvent)[Pathway:141334] PAOs oxidise polyamines to amines [Homo sapiens]
[Pathway:351200] Interconversion of polyamines [Homo sapiens]
(updatedInstance)[_UpdateTracker:9786193] Update Tracker - [Reaction:141351] PAOX:FAD oxidises NASPN to SPM - v50:[modifyText]
[_UpdateTracker:9791786] Update Tracker - [Reaction:141351] PAOX:FAD oxidises NASPN to SPM - v25:[addLiteratureReference, modifyText]
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