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Details on Person FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

Class:IdLiteratureReference:141128
_displayNameFADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
_timestamp2004-09-02 19:09:37
author[Person:141131] Sprick, MR
[Person:141129] Weigand, MA
[Person:141136] Rieser, E
[Person:141130] Rauch, CT
[Person:141135] Juo, P
[Person:141134] Blenis, J
[Person:140498] Krammer, PH
[Person:141138] Walczak, H
created[InstanceEdit:141132] Gillespie, ME, 2004-09-02 19:09:36
journalImmunity
pages599-609
pubMedIdentifier10894160
titleFADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
volume12
year2000
(literatureReference)[Summation:179245] The trimeric complex of TRAIL and TRAIL receptor-1 (TNFSF10:...
[Summation:179247] FADD recruits caspase-8 precursor to trimeric complex of TRA...
[Summation:179273] The complex of TRAIL (TNFSF10) and TRAIL receptor-1 (TNFRSF1...
[Complex:141126] TNFSF10:TNFRSF10B Trimer [plasma membrane] [Homo sapiens]
[Complex:141133] TNFSF10:TNFRSF10B:FADD:CASP8(1-479) [plasma membrane] [Homo sapiens]
[Complex:141137] TNFSF10:TNFRSF10B:FADD [plasma membrane] [Homo sapiens]
[Complex:5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] [Homo sapiens]
[Complex:5637468] TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] [Homo sapiens]
[Complex:5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane] [Homo sapiens]
[Reaction:75146] TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 [Homo sapiens]
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No pathways have been reviewed or authored by FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 (141128)