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Details on Person Activated protein C [extracellular region]

Class:Id	Complex:141050
_displayName	Activated protein C [extracellular region]
_timestamp	2014-07-02 12:28:57
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:140993] D'Eustachio, P, 2004-08-26 13:13:00
hasComponent	[EntityWithAccessionedSequence:141041] 8xCbxE-3D-PROC(43-197) [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:141048] PROC(212-461) [extracellular region] [Homo sapiens] [SimpleEntity:74112] Ca2+ [extracellular region]
literatureReference	[LiteratureReference:141018] Characterization of a cDNA coding for human protein C [LiteratureReference:141016] Endoproteolytic processing of the dibasic cleavage site in the human protein C precursor in transfected mammalian cells: effects of sequence alterations on efficiency of cleavage [LiteratureReference:141045] Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombin
modified	[InstanceEdit:5603471] Jupe, Steve, 2014-07-02
name	Activated protein C
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:370623] R-HSA-141050.1
(activeUnit)	[CatalystActivity:141025] serine-type endopeptidase activity of Activated protein C:Protein S [plasma membrane]
(hasComponent)	[Complex:5603469] PROCR:Activated protein C [plasma membrane] [Homo sapiens] [Complex:5604926] Activated protein C:Protein S [plasma membrane] [Homo sapiens] [Complex:5607007] SERPINA5:Activated protein C [extracellular region] [Homo sapiens] [Complex:5610097] PROCR(18-?):Activated protein C [extracellular region] [Homo sapiens]
(input)	[Reaction:5591086] SERPINA5 binds activated protein C [Homo sapiens] [Reaction:5604929] Activated protein C binds Protein S [Homo sapiens] [Reaction:5606996] Soluble PROCR binds activated protein C [Homo sapiens]
(output)	[Reaction:5603467] Activated protein C is released from PROCR [Homo sapiens]
(physicalEntity)	[CatalystActivity:5607101] serine-type endopeptidase activity of Activated protein C [extracellular region]
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No pathways have been reviewed or authored by Activated protein C [extracellular region] (141050)