Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person OBSOLETE_factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst)_REPLACEMENT_9929051_9929054

Class:Id	Reaction:140823
_displayName	OBSOLETE_factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst)_REPLACEMENT_9929051_9929054
_doRelease	FALSE
_timestamp	2026-01-20 07:25:46
authored	[InstanceEdit:140579] D'Eustachio, P, 2004-08-24 14:00:00
catalystActivity	[CatalystActivity:140735] serine-type endopeptidase activity of TF:FVIIa [plasma membrane]
catalystActivityReference	[CatalystActivityReference:9671240] serine-type endopeptidase activity of TF:F7a [plasma membrane] Proteolytic activation of human factors IX and X by recombinant human factor VIIa: effects of calcium, phospholipids, and tissue factor
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:140579] D'Eustachio, P, 2004-08-24 14:00:00
input	[EntityWithAccessionedSequence:140886] 12xCbxE-3D-F9(47-461) [extracellular region] [Homo sapiens]
literatureReference	[LiteratureReference:140892] Cooperative activation of human factor IX by the human extrinsic pathway of blood coagulation [LiteratureReference:140741] Proteolytic activation of human factors IX and X by recombinant human factor VIIa: effects of calcium, phospholipids, and tissue factor
modified	[InstanceEdit:142088] Schmidt, EE, 2004-11-04 17:13:34 [InstanceEdit:158298] D'Eustachio, P, 2005-01-20 14:44:36 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9671241] Shamovsky, Veronica, 2019-12-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9979521] Shamovsky, Veronica, 2026-01-20
name	OBSOLETE_factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst)_REPLACEMENT_9929051_9929054 activation of factor IX (TF:F7a catalyst)
output	[Complex:140896] factor IXa [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:140897] factor IX activation peptide [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:140748] tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex [Homo sapiens] [Reaction:140761] sequestered tissue factor -> tissue factor [Homo sapiens] [Reaction:140769] factor VII -> factor VIIa [Homo sapiens]
regulatedBy	[PositiveRegulation:158643] Positive regulation by 'Ca2+ [extracellular region]'
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358650] R-HSA-140823.4
summation	[Summation:140891] Conversion of factor IX (FIX) to FIXa requires proteolytic c...
(hasEvent)	[Pathway:140834] OBSOLETE_Extrinsic Pathway of Fibrin Clot Formation_REPLACEMENT_9769735 [Homo sapiens] [Pathway:9769735] Initiation of coagulation cascade [Homo sapiens]
(precedingEvent)	[Reaction:158278] factor VIIIa + factor IXa -> factor VIIIa:factor IXa [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9777120] Update Tracker - [Reaction:140823] factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) - v72:[addRegulator, modifyText] [_UpdateTracker:9939753] Update Tracker - [Reaction:140823] factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) - v92:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by OBSOLETE_factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst)_REPLACEMENT_9929051_9929054 (140823)