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Details on Person Activated thrombin cleaves the A chains of factor XIII tetra...
| Class:Id | Summation:140609 |
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| _displayName | Activated thrombin cleaves the A chains of factor XIII tetra... |
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| _timestamp | 2017-10-26 08:10:45 |
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| created | [InstanceEdit:140579] D'Eustachio, P, 2004-08-24 14:00:00 |
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| literatureReference | [LiteratureReference:140610] Regulation of formation of factor XIIIa by its fibrin substrates |
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| modified | [InstanceEdit:9015392] Jassal, Bijay, 2017-08-10
[InstanceEdit:9015703] Jassal, Bijay, 2017-08-11
[InstanceEdit:9015707] Jassal, Bijay, 2017-08-11
[InstanceEdit:9026995] Jassal, Bijay, 2017-10-25
[InstanceEdit:9027000] Jassal, Bijay, 2017-10-26 |
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| text | Activated thrombin cleaves the A chains of factor XIII tetramers in a reaction stimulated by the presence of fibrin multimers (Lewis et al. 1985). The amino terminal portions of the A chains are released as activation peptides, which have no known function. The resulting factor XIII tetramer remains catalytically inactive. |
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| (summation) | [Reaction:140599] factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides [Homo sapiens] |
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